ID	Name	Namespace	Distance
2.7.3	Phosphotransferases with a nitrogenous group as ac	enzyme_commission	3
2.7.3.9	Phosphoenolpyruvate--protein phosphotransferase	enzyme_commission	4
2.7	Transferring phosphorous-containing groups	enzyme_commission	2
2	Transferases	enzyme_commission	1
6	Ligases	enzyme_commission	1
6.1.1.2	Tryptophan--tRNA ligase	enzyme_commission	4
6.1.1	Ligases forming aminoacyl-tRNA and related compoun	enzyme_commission	3
6.1	Forming carbon-oxygen bonds	enzyme_commission	2
2.7.6.3	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine 	enzyme_commission	4
2.5.1.15	Dihydropteroate synthase	enzyme_commission	4
2.7.6	Diphosphotransferases	enzyme_commission	3
2.5.1	Transferring alkyl or aryl groups, other than meth	enzyme_commission	3
1	Oxidoreductases	enzyme_commission	1
2.1.1.13	Methionine synthase	enzyme_commission	4
2.5	Transferring alkyl or aryl groups, other than meth	enzyme_commission	2
1.17.7.1	(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synth	enzyme_commission	4
2.1.1.86	Tetrahydromethanopterin S-methyltransferase	enzyme_commission	4
1.17	Acting on CH or CH(2) groups	enzyme_commission	2
2.1.1	Methyltransferases	enzyme_commission	3
2.1	Transferring one-carbon groups	enzyme_commission	2
1.17.7	With an iron-sulfur protein as acceptor	enzyme_commission	3
6.3.4.14	Biotin carboxylase	enzyme_commission	4
4.1.1.21	Phosphoribosylaminoimidazole carboxylase	enzyme_commission	4
6.4.1.1	Pyruvate carboxylase	enzyme_commission	4
6.3.3	Cyclo-ligases	enzyme_commission	3
6.4.1	Ligases that form carbon-carbon bonds	enzyme_commission	3
6.4.1.4	Methylcrotonoyl-CoA carboxylase	enzyme_commission	4
6.3.3.1	Phosphoribosylformylglycinamidine cyclo-ligase	enzyme_commission	4
6.3	Forming carbon-nitrogen bonds	enzyme_commission	2
4.1	Carbon-carbon lyases	enzyme_commission	2
4.1.1	Carboxy-lyases	enzyme_commission	3
6.4	Forming carbon-carbon bonds	enzyme_commission	2
2.1.2.2	Phosphoribosylglycinamide formyltransferase	enzyme_commission	4
6.3.4	Other carbon--nitrogen ligases	enzyme_commission	3
4	Lyases	enzyme_commission	1
6.3.4.18	5-(carboxyamino)imidazole ribonucleotide synthase	enzyme_commission	4
2.1.2	Hydroxymethyl-, formyl- and related transferases	enzyme_commission	3
6.3.4.13	Phosphoribosylamine--glycine ligase	enzyme_commission	4
5.4.2.2	Phosphoglucomutase	enzyme_commission	4
5.4.2	Phosphotransferases (phosphomutases)	enzyme_commission	3
5.4.2.10	Phosphoglucosamine mutase	enzyme_commission	4
5.4	Intramolecular transferases (mutases)	enzyme_commission	2
5	Isomerases	enzyme_commission	1
5.1	Racemases and epimerases	enzyme_commission	2
2.4.1.21	Starch synthase	enzyme_commission	4
2.4.1.182	Lipid-A-disaccharide synthase	enzyme_commission	4
2.4	Glycosyltransferases	enzyme_commission	2
2.4.1.227	acetylglucosaminyltransferase	enzyme_commission	4
5.1.3.14	UDP-N-acetylglucosamine 2-epimerase	enzyme_commission	4
5.1.3	Acting on carbohydrates and derivatives	enzyme_commission	3
2.4.1	Hexosyltransferases	enzyme_commission	3
2.4.1.17	Glucuronosyltransferase	enzyme_commission	4
3.2	Glycosylases	enzyme_commission	2
3.5.1	In linear amides	enzyme_commission	3
3.5.1.28	N-acetylmuramoyl-L-alanine amidase	enzyme_commission	4
3.5	Acting on carbon-nitrogen bonds, other than peptid	enzyme_commission	2
3	Hydrolases	enzyme_commission	1
3.2.1	Glycosidases, i.e. enzymes hydrolyzing O- and S-gl	enzyme_commission	3
3.2.1.96	Mannosyl-glycoprotein endo-beta-N-acetylglucosamin	enzyme_commission	4
2.7.11.25	Mitogen-activated protein kinase kinase kinase	enzyme_commission	4
3.1.4.11	Phosphoinositide phospholipase C	enzyme_commission	4
2.7.10	Protein-tyrosine kinases	enzyme_commission	3
2.4.1.68	Glycoprotein 6-alpha-L-fucosyltransferase	enzyme_commission	4
3.1.4	Phosphoric diester hydrolases	enzyme_commission	3
2.7.11	Protein-serine/threonine kinases	enzyme_commission	3
3.1	Acting on ester bonds	enzyme_commission	2
2.7.10.2	Non-specific protein-tyrosine kinase	enzyme_commission	4
4.2.3	Acting on phosphates	enzyme_commission	3
2.7.1.71	Shikimate kinase	enzyme_commission	4
4.2	Carbon-oxygen lyases	enzyme_commission	2
1.1.1.25	Shikimate dehydrogenase	enzyme_commission	4
2.5.1.19	3-phosphoshikimate 1-carboxyvinyltransferase	enzyme_commission	4
6.5.1	Ligases that form phosphoric-ester bonds	enzyme_commission	3
6.5.1.4	RNA-3'-phosphate cyclase	enzyme_commission	4
1.1	Acting on the CH-OH group of donors	enzyme_commission	2
4.2.3.4	3-dehydroquinate synthase	enzyme_commission	4
4.2.1	Hydro-lyases	enzyme_commission	3
6.5	Forming phosphoric ester bonds	enzyme_commission	2
4.2.1.10	3-dehydroquinate dehydratase	enzyme_commission	4
2.5.1.7	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	enzyme_commission	4
2.7.1	Phosphotransferases with an alcohol group as accep	enzyme_commission	3
1.1.1	With NAD(+) or NADP(+) as acceptor	enzyme_commission	3
2.7.11.2	[Pyruvate dehydrogenase (acetyl-transferring)] kin	enzyme_commission	4
1.2.4.1	Pyruvate dehydrogenase (acetyl-transferring)	enzyme_commission	4
1.2.4	With a disulfide as acceptor	enzyme_commission	3
2.2	Transferring aldehyde or ketone residues	enzyme_commission	2
1.2	Acting on the aldehyde or oxo group of donors	enzyme_commission	2
2.2.1.7	1-deoxy-D-xylulose-5-phosphate synthase	enzyme_commission	4
1.2.7	With an iron-sulfur protein as acceptor	enzyme_commission	3
2.2.1	Transketolases and transaldolases	enzyme_commission	3
2.2.1.1	Transketolase	enzyme_commission	4
1.14.18	With another compound as one donor, and incorporat	enzyme_commission	3
1.14.18.1	Monophenol monooxygenase	enzyme_commission	4
1.14	Acting on paired donors, with incorporation or red	enzyme_commission	2
2.7.7.65	Diguanylate cyclase	enzyme_commission	4
1.14.12.17	Nitric oxide dioxygenase	enzyme_commission	4
2.7.7	Nucleotidyltransferases	enzyme_commission	3
1.14.12	With NADH or NADPH as one donor, and incorporation	enzyme_commission	3
2.3	Acyltransferases	enzyme_commission	2
2.3.1.101	Formylmethanofuran--tetrahydromethanopterin N-form	enzyme_commission	4
2.3.1	Transferring groups other than amino-acyl groups	enzyme_commission	3
2.7.11.1	Non-specific serine/threonine protein kinase	enzyme_commission	4
3.4	Acting on peptide bonds (peptide hydrolases)	enzyme_commission	2
3.4.22	Cysteine endopeptidases	enzyme_commission	3
3.4.22.36	Caspase-1	enzyme_commission	4
1.6.5	With a quinone or similar compound as acceptor	enzyme_commission	3
1.6.5.3	NADH:ubiquinone reductase (H(+)-translocating)	enzyme_commission	4
1.12	Acting on hydrogen as donor	enzyme_commission	2
1.6	Acting on NADH or NADPH	enzyme_commission	2
1.6.99	With other acceptors	enzyme_commission	3
1.6.99.5	NADH dehydrogenase (quinone)	enzyme_commission	4
3.2.1.3	Glucan 1,4-alpha-glucosidase	enzyme_commission	4
3.2.1.41	Pullulanase	enzyme_commission	4
4.2.2	Acting on polysaccharides	enzyme_commission	3
3.2.1.1	Alpha-amylase	enzyme_commission	4
4.2.2.23	Rhamnogalacturonan endolyase	enzyme_commission	4
2.4.1.19	Cyclomaltodextrin glucanotransferase	enzyme_commission	4
1.9	Acting on a heme group of donors	enzyme_commission	2
3.1.1	Carboxylic ester hydrolases	enzyme_commission	3
3.1.1.5	Lysophospholipase	enzyme_commission	4
2.7.11.12	cGMP-dependent protein kinase	enzyme_commission	4
2.7.11.18	[Myosin light-chain] kinase	enzyme_commission	4
1.11.1.7	Peroxidase	enzyme_commission	4
1.11	Acting on a peroxide as acceptor	enzyme_commission	2
1.11.1	Peroxidases	enzyme_commission	3
2.7.10.1	Receptor protein-tyrosine kinase	enzyme_commission	4
3.1.3.48	Protein-tyrosine-phosphatase	enzyme_commission	4
3.1.3	Phosphoric monoester hydrolases	enzyme_commission	3
4.2.1.49	Urocanate hydratase	enzyme_commission	4
1.14.11.4	Procollagen-lysine 5-dioxygenase	enzyme_commission	4
2.7.7.13	Mannose-1-phosphate guanylyltransferase	enzyme_commission	4
2.7.7.60	2-C-methyl-D-erythritol 4-phosphate cytidylyltrans	enzyme_commission	4
2.7.7.9	UTP--glucose-1-phosphate uridylyltransferase	enzyme_commission	4
1.14.11	With 2-oxoglutarate as one donor, and incorporatio	enzyme_commission	3
2.4.1.175	acetylgalactosaminyltransferase	enzyme_commission	4
2.4.1.16	Chitin synthase	enzyme_commission	4
2.4.1.228	Lactosylceramide 4-alpha-galactosyltransferase	enzyme_commission	4
2.4.1.38	Beta-N-acetylglucosaminylglycopeptide beta-1,4-gal	enzyme_commission	4
4.6.1.12	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synth	enzyme_commission	4
2.4.1.22	Lactose synthase	enzyme_commission	4
2.7.7.68	2-phospho-L-lactate guanylyltransferase	enzyme_commission	4
4.6.1	Phosphorus-oxygen lyases	enzyme_commission	3
2.4.1.226	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuro	enzyme_commission	4
5.4.99	Transferring other groups	enzyme_commission	3
2.4.1.12	Cellulose synthase (UDP-forming)	enzyme_commission	4
5.3.1.8	Mannose-6-phosphate isomerase	enzyme_commission	4
5.3.1	Interconverting aldoses and ketoses, and related c	enzyme_commission	3
2.4.1.90	N-acetyllactosamine synthase	enzyme_commission	4
4.6	Phosphorus-oxygen lyases	enzyme_commission	2
2.7.7.27	Glucose-1-phosphate adenylyltransferase	enzyme_commission	4
5.4.99.30	UDP-arabinopyranose mutase	enzyme_commission	4
2.4.1.225	N-acetylglucosaminyl-proteoglycan 4-beta-glucurono	enzyme_commission	4
2.4.1.41	Polypeptide N-acetylgalactosaminyltransferase	enzyme_commission	4
5.3	Intramolecular oxidoreductases	enzyme_commission	2
2.4.1.212	Hyaluronan synthase	enzyme_commission	4
2.4.1.186	Glycogenin glucosyltransferase	enzyme_commission	4
2.4.1.87	N-acetyllactosaminide 3-alpha-galactosyltransferas	enzyme_commission	4
2.7.8.30	Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabi	enzyme_commission	4
2.4.1.135	Galactosylgalactosylxylosylprotein 3-beta-glucuron	enzyme_commission	4
2.4.1.80	Ceramide glucosyltransferase	enzyme_commission	4
2.4.1.101	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglu	enzyme_commission	4
2.7.7.43	N-acylneuraminate cytidylyltransferase	enzyme_commission	4
2.7.7.23	UDP-N-acetylglucosamine diphosphorylase	enzyme_commission	4
2.3.1.157	Glucosamine-1-phosphate N-acetyltransferase	enzyme_commission	4
2.4.1.83	Dolichyl-phosphate beta-D-mannosyltransferase	enzyme_commission	4
2.4.1.117	Dolichyl-phosphate beta-glucosyltransferase	enzyme_commission	4
2.7.7.24	Glucose-1-phosphate thymidylyltransferase	enzyme_commission	4
2.4.1.50	Procollagen galactosyltransferase	enzyme_commission	4
2.7.7.38	3-deoxy-manno-octulosonate cytidylyltransferase	enzyme_commission	4
2.4.1.223	acetylglucosaminyltransferase	enzyme_commission	4
2.4.1.224	acetylglucosaminyltransferase	enzyme_commission	4
2.7.7.64	UTP-monosaccharide-1-phosphate uridylyltransferase	enzyme_commission	4
2.7.8	Transferases for other substituted phosphate group	enzyme_commission	3
2.7.13	Protein-histidine kinases	enzyme_commission	3
3.5.1.88	Peptide deformylase	enzyme_commission	4
4.2.2.1	Hyaluronate lyase	enzyme_commission	4
1.8	Acting on a sulfur group of donors	enzyme_commission	2
2.1.1.57	mRNA (nucleoside-2'-O-)-methyltransferase	enzyme_commission	4
3.6.1	In phosphorous-containing anhydrides	enzyme_commission	3
2.3.2	Aminoacyltransferases	enzyme_commission	3
3.6.4	Acting on acid anhydrides; involved in cellular an	enzyme_commission	3
1.8.3.1	Sulfite oxidase	enzyme_commission	4
2.1.1.56	mRNA (guanine-N(7)-)-methyltransferase	enzyme_commission	4
1.7	Acting on other nitrogenous compounds as donors	enzyme_commission	2
1.7.1	With NAD(+) or NADP(+) as acceptor	enzyme_commission	3
3.4.21.90	Togavirin	enzyme_commission	4
1.8.3	With oxygen as acceptor	enzyme_commission	3
3.4.21	Serine endopeptidases	enzyme_commission	3
3.4.21.91	Flavivirin	enzyme_commission	4
3.2.1.68	Isoamylase	enzyme_commission	4
3.6.1.15	Nucleoside-triphosphatase	enzyme_commission	4
1.7.1.3	Nitrate reductase (NADPH)	enzyme_commission	4
3.6.4.13	RNA helicase	enzyme_commission	4
2.4.1.18	1,4-alpha-glucan branching enzyme	enzyme_commission	4
2.3.2.13	Protein-glutamine gamma-glutamyltransferase	enzyme_commission	4
1.7.1.1	Nitrate reductase (NADH)	enzyme_commission	4
3.6	Acting on acid anhydrides	enzyme_commission	2
2.7.7.48	RNA-directed RNA polymerase	enzyme_commission	4
3.2.1.141	4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehal	enzyme_commission	4
2.3.1.176	Propanoyl-CoA C-acyltransferase	enzyme_commission	4
3.6.5.5	Dynamin GTPase	enzyme_commission	4
2.7.11.15	[Beta-adrenergic-receptor] kinase	enzyme_commission	4
2.7.1.107	Diacylglycerol kinase	enzyme_commission	4
3.6.5	Acting on GTP; involved in cellular and subcellula	enzyme_commission	3
3.1.3.64	Phosphatidylinositol-3-phosphatase	enzyme_commission	4
2.4.1.173	Sterol 3-beta-glucosyltransferase	enzyme_commission	4
2.7.11.13	Protein kinase C	enzyme_commission	4
6.5.1.1	DNA ligase (ATP)	enzyme_commission	4
1.3.99.10	Isovaleryl-CoA dehydrogenase	enzyme_commission	4
1.3.8.1	Butyryl-CoA dehydrogenase	enzyme_commission	4
1.3.8	With a flavin as acceptor	enzyme_commission	3
1.3.3.6	Acyl-CoA oxidase	enzyme_commission	4
1.3	Acting on the CH-CH group of donors	enzyme_commission	2
1.3.99.3	Acyl-CoA dehydrogenase	enzyme_commission	4
1.14.14.9	4-hydroxyphenylacetate 3-monooxygenase	enzyme_commission	4
1.14.14	With reduced flavin or flavoprotein as one donor, 	enzyme_commission	3
1.3.99	With other acceptors	enzyme_commission	3
1.3.3	With oxygen as acceptor	enzyme_commission	3
3.1.27.9	tRNA-intron endonuclease	enzyme_commission	4
3.1.27	Endoribonucleases producing other than 5'-phosphom	enzyme_commission	3
3.2.1.78	Mannan endo-1,4-beta-mannosidase	enzyme_commission	4
3.2.1.91	Cellulose 1,4-beta-cellobiosidase (non-reducing en	enzyme_commission	4
3.2.1.4	Cellulase	enzyme_commission	4
2.3.1.51	1-acylglycerol-3-phosphate O-acyltransferase	enzyme_commission	4
2.3.1.42	Glycerone-phosphate O-acyltransferase	enzyme_commission	4
2.3.1.67	1-alkylglycerophosphocholine O-acetyltransferase	enzyme_commission	4
6.2	Forming carbon-sulfur bonds	enzyme_commission	2
2.3.1.23	1-acylglycerophosphocholine O-acyltransferase	enzyme_commission	4
2.3.1.40	Acyl-[acyl-carrier-protein]--phospholipid O-acyltr	enzyme_commission	4
2.3.1.15	Glycerol-3-phosphate O-acyltransferase	enzyme_commission	4
6.2.1.20	Long-chain-fatty-acid--[acyl-carrier-protein] liga	enzyme_commission	4
6.2.1	Acid--thiol ligases	enzyme_commission	3
3.5.3	In linear amidines	enzyme_commission	3
1.7.2.4	Nitrous-oxide reductase	enzyme_commission	4
1.7.2.1	Nitrite reductase (NO-forming)	enzyme_commission	4
1.10.3	With oxygen as acceptor	enzyme_commission	3
3.5.3.15	Protein-arginine deiminase	enzyme_commission	4
1.10	Acting on diphenols and related substances as dono	enzyme_commission	2
1.10.3.2	Laccase	enzyme_commission	4
1.7.2	With a cytochrome as acceptor	enzyme_commission	3
3.1.3.11	Fructose-bisphosphatase	enzyme_commission	4
3.1.3.57	Inositol-1,4-bisphosphate 1-phosphatase	enzyme_commission	4
3.1.3.37	Sedoheptulose-bisphosphatase	enzyme_commission	4
3.1.3.25	Inositol-phosphate phosphatase	enzyme_commission	4
3.1.3.7	3'(2'),5'-bisphosphate nucleotidase	enzyme_commission	4
3.1.1.26	Galactolipase	enzyme_commission	4
3.1.1.34	Lipoprotein lipase	enzyme_commission	4
1.13.11.12	Linoleate 13S-lipoxygenase	enzyme_commission	4
1.13	Acting on single donors with incorporation of mole	enzyme_commission	2
1.13.11.33	Arachidonate 15-lipoxygenase	enzyme_commission	4
1.13.11.58	Linoleate 9S-lipoxygenase	enzyme_commission	4
3.1.1.3	Triacylglycerol lipase	enzyme_commission	4
1.13.11	With incorporation of two atoms of oxygen	enzyme_commission	3
3.1.4.3	Phospholipase C	enzyme_commission	4
1.13.11.31	Arachidonate 12-lipoxygenase	enzyme_commission	4
2.7.1.31	Glycerate kinase	enzyme_commission	4
3.5.1.9	Arylformamidase	enzyme_commission	4
1.3.5	With a quinone or related compound as acceptor	enzyme_commission	3
1.3.99.1	Succinate dehydrogenase	enzyme_commission	4
1.3.5.1	Succinate dehydrogenase (ubiquinone)	enzyme_commission	4
1.4.3	With oxygen as acceptor	enzyme_commission	3
1.4	Acting on the CH-NH(2) group of donors	enzyme_commission	2
1.4.3.16	L-aspartate oxidase	enzyme_commission	4
3.6.4.12	DNA helicase	enzyme_commission	4
2.7.11.17	Calcium/calmodulin-dependent protein kinase	enzyme_commission	4
5.2	Cis-trans-isomerases	enzyme_commission	2
1.6.3	With a oxygen as acceptor	enzyme_commission	3
1.1.5	With a quinone or similar compound as acceptor	enzyme_commission	3
3.4.22.54	Calpain-3	enzyme_commission	4
2.2.1.2	Transaldolase	enzyme_commission	4
5.2.1	Cis-trans Isomerases	enzyme_commission	3
3.4.21.105	Rhomboid protease	enzyme_commission	4
1.1.5.3	Glycerol-3-phosphate dehydrogenase	enzyme_commission	4
5.2.1.8	Peptidylprolyl isomerase	enzyme_commission	4
3.4.22.53	Calpain-2	enzyme_commission	4
3.1.3.16	Phosphoprotein phosphatase	enzyme_commission	4
3.4.22.52	Calpain-1	enzyme_commission	4
1.3.1.9	Enoyl-[acyl-carrier-protein] reductase (NADH)	enzyme_commission	4
2.3.1.41	Beta-ketoacyl-acyl-carrier-protein synthase I	enzyme_commission	4
3.1.2.14	Oleoyl-[acyl-carrier-protein] hydrolase	enzyme_commission	4
2.3.1.85	Fatty-acid synthase	enzyme_commission	4
2.3.1.86	Fatty-acyl-CoA synthase	enzyme_commission	4
2.3.1.39	[Acyl-carrier-protein] S-malonyltransferase	enzyme_commission	4
1.3.1.10	Enoyl-[acyl-carrier-protein] reductase (NADPH, B-s	enzyme_commission	4
1.1.1.100	3-oxoacyl-[acyl-carrier-protein] reductase	enzyme_commission	4
3.1.2	Thiolester hydrolases	enzyme_commission	3
1.3.1	With NAD(+) or NADP(+) as acceptor	enzyme_commission	3
4.2.1.61	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydrat	enzyme_commission	4
2.3.1.38	[Acyl-carrier-protein] S-acetyltransferase	enzyme_commission	4
5.99	Other isomerases	enzyme_commission	2
5.99.1	Sole sub-subclass for isomerases that do not belon	enzyme_commission	3
5.99.1.2	DNA topoisomerase	enzyme_commission	4
3.5.2.7	Imidazolonepropionase	enzyme_commission	4
3.5.4	In cyclic amidines	enzyme_commission	3
3.5.1.5	Urease	enzyme_commission	4
3.5.4.3	Guanine deaminase	enzyme_commission	4
3.5.4.2	Adenine deaminase	enzyme_commission	4
3.5.4.31	S-methyl-5'-thioadenosine deaminase	enzyme_commission	4
3.5.2	In cyclic amides	enzyme_commission	3
3.5.4.28	S-adenosylhomocysteine deaminase	enzyme_commission	4
3.5.1.25	N-acetylglucosamine-6-phosphate deacetylase	enzyme_commission	4
5.4.2.1	Phosphoglycerate mutase	enzyme_commission	4
2.7.7.59	[Protein-PII] uridylyltransferase	enzyme_commission	4
2.7.7.42	[Glutamate--ammonia-ligase] adenylyltransferase	enzyme_commission	4
3.2.1.23	Beta-galactosidase	enzyme_commission	4
2.4.1.25	4-alpha-glucanotransferase	enzyme_commission	4
2.4.1.n5	Starch synthase (maltosyl-transferring)	enzyme_commission	4
3.2.1.58	Glucan 1,3-beta-glucosidase	enzyme_commission	4
3.2.1.85	6-phospho-beta-galactosidase	enzyme_commission	4
3.2.1.21	Beta-glucosidase	enzyme_commission	4
2.4.1.5	Dextransucrase	enzyme_commission	4
3.2.1.39	Glucan endo-1,3-beta-D-glucosidase	enzyme_commission	4
2.4.1.82	Galactinol--sucrose galactosyltransferase	enzyme_commission	4
3.2.1.52	Beta-N-acetylhexosaminidase	enzyme_commission	4
3.2.1.20	Alpha-glucosidase	enzyme_commission	4
3.1.3.2	Acid phosphatase	enzyme_commission	4
2.5.1.17	Cob(I)yrinic acid a,c-diamide adenosyltransferase	enzyme_commission	4
3.6.1.9	Nucleotide diphosphatase	enzyme_commission	4
3.1.4.1	Phosphodiesterase I	enzyme_commission	4
1.1.1.22	UDP-glucose 6-dehydrogenase	enzyme_commission	4
1.1.1.132	GDP-mannose 6-dehydrogenase	enzyme_commission	4
1.1.1.n3	UDP-N-acetyl-D-mannosamine dehydrogenase	enzyme_commission	4
4.1.1.20	Diaminopimelate decarboxylase	enzyme_commission	4
4.1.1.17	Ornithine decarboxylase	enzyme_commission	4
4.1.1.19	Arginine decarboxylase	enzyme_commission	4
5.1.1	Acting on amino acids and derivatives	enzyme_commission	3
5.1.1.1	Alanine racemase	enzyme_commission	4
2.4.2.21	Nicotinate-nucleotide--dimethylbenzimidazole phosp	enzyme_commission	4
2.4.2	Pentosyltransferases	enzyme_commission	3
6.5.1.2	DNA ligase (NAD(+))	enzyme_commission	4
3.4.21.68	T-plasminogen activator	enzyme_commission	4
1.17.4.1	Ribonucleoside-diphosphate reductase	enzyme_commission	4
1.17.4	With a disulfide as acceptor	enzyme_commission	3
3.1.26.5	Ribonuclease P	enzyme_commission	4
3.1.26	Endoribonucleases producing 5'-phosphomonoesters	enzyme_commission	3
2.7.1.160	2'-phosphotransferase	enzyme_commission	4
2.4.2.36	NAD(+)--diphthamide ADP-ribosyltransferase	enzyme_commission	4
2.4.2.30	NAD(+) ADP-ribosyltransferase	enzyme_commission	4
2.7.1.67	1-phosphatidylinositol 4-kinase	enzyme_commission	4
2.4.2.31	NAD(+)--protein-arginine ADP-ribosyltransferase	enzyme_commission	4
2.7.7.7	DNA-directed DNA polymerase	enzyme_commission	4
5.3.99	Other intramolecular oxidoreductases	enzyme_commission	3
5.3.99.2	Prostaglandin-D synthase	enzyme_commission	4
2.7.4.1	Polyphosphate kinase	enzyme_commission	4
2.7.4	Phosphotransferases with a phosphate group as acce	enzyme_commission	3
4.2.99	Other carbon-oxygen lyases	enzyme_commission	3
4.2.99.18	DNA-(apurinic or apyrimidinic site) lyase	enzyme_commission	4
3.2.2	Hydrolyzing N-glycosyl compounds	enzyme_commission	3
3.2.2.23	DNA-formamidopyrimidine glycosylase	enzyme_commission	4
2.7.1.21	Thymidine kinase	enzyme_commission	4
3.4.22.44	Nuclear-inclusion-a endopeptidase	enzyme_commission	4
3.4.23.47	HIV-2 retropepsin	enzyme_commission	4
3.4.21.98	Hepacivirin	enzyme_commission	4
3.1.26.13	Retroviral ribonuclease H	enzyme_commission	4
3.4.22.45	Helper-component proteinase	enzyme_commission	4
2.7.7.49	RNA-directed DNA polymerase	enzyme_commission	4
3.4.22.28	Picornain 3C	enzyme_commission	4
3.1.3.33	Polynucleotide 5'-phosphatase	enzyme_commission	4
3.4.22.66	Calicivirin	enzyme_commission	4
3.4.22.29	Picornain 2A	enzyme_commission	4
3.4.19	Omega peptidases	enzyme_commission	3
3.4.23.16	HIV-1 retropepsin	enzyme_commission	4
3.1.13	Exoribonucleases producing 5'-phosphomonoesters	enzyme_commission	3
3.1.26.4	Ribonuclease H	enzyme_commission	4
3.1.13.2	Exoribonuclease H	enzyme_commission	4
3.4.23	Aspartic endopeptidases	enzyme_commission	3
3.4.19.12	Ubiquitinyl hydrolase 1	enzyme_commission	4
3.4.21.113	Pestivirus NS3 polyprotein peptidase	enzyme_commission	4
5.3.4	Transposing S-S bonds	enzyme_commission	3
5.2.1.2	Maleylacetoacetate isomerase	enzyme_commission	4
1.8.1	With NAD(+) or NADP(+) as acceptor	enzyme_commission	3
1.8.5.1	Glutathione dehydrogenase (ascorbate)	enzyme_commission	4
1.11.1.12	Phospholipid-hydroperoxide glutathione peroxidase	enzyme_commission	4
1.8.1.8	Protein-disulfide reductase	enzyme_commission	4
1.8.5	With a quinone or similar compound as acceptor	enzyme_commission	3
4.5	Carbon-halide lyases	enzyme_commission	2
2.5.1.18	Glutathione transferase	enzyme_commission	4
1.11.1.20	Prostamide/prostaglandin F(2-alpha) synthase	enzyme_commission	4
1.11.1.15	Peroxiredoxin	enzyme_commission	4
1.97.1	Sole sub-subclass for oxidoreductases that do not 	enzyme_commission	3
1.97.1.11	Thyroxine 5-deiodinase	enzyme_commission	4
1.6.99.3	NADH dehydrogenase	enzyme_commission	4
1.20	Acting on phosphorus or arsenic in donors	enzyme_commission	2
1.97	Other oxidoreductases	enzyme_commission	2
1.11.1.9	Glutathione peroxidase	enzyme_commission	4
1.8.3.2	Thiol oxidase	enzyme_commission	4
1.20.4	With disulfide as acceptor	enzyme_commission	3
1.97.1.10	Thyroxine 5'-deiodinase	enzyme_commission	4
3.6.1.23	dUTP diphosphatase	enzyme_commission	4
3.4.13.9	Xaa-Pro dipeptidase	enzyme_commission	4
3.4.11	Aminopeptidases	enzyme_commission	3
3.4.11.9	Xaa-Pro aminopeptidase	enzyme_commission	4
3.4.13	Dipeptidases	enzyme_commission	3
4.2.1.75	Uroporphyrinogen-III synthase	enzyme_commission	4
2.5.1.6	Methionine adenosyltransferase	enzyme_commission	4
2.5.1.46	Deoxyhypusine synthase	enzyme_commission	4
1.6.1	With NAD(+) or NADP(+) as acceptor	enzyme_commission	3
4.1.1.1	Pyruvate decarboxylase	enzyme_commission	4
2.2.1.6	Acetolactate synthase	enzyme_commission	4
3.7	Acting on carbon-carbon bonds	enzyme_commission	2
1.6.1.2	NAD(P)(+) transhydrogenase (AB-specific)	enzyme_commission	4
3.7.1.n2	3,5/4-trihydroxycyclohexa-1,2-dione hydrolase	enzyme_commission	4
3.7.1	In ketonic substances	enzyme_commission	3
2.2.1.9	synthase	enzyme_commission	4
4.3.2	Lyases acting on amides, amidines, etc	enzyme_commission	3
4.3	Carbon-nitrogen lyases	enzyme_commission	2
4.3.2.5	Peptidylamidoglycolate lyase	enzyme_commission	4
1.14.17.3	Peptidylglycine monooxygenase	enzyme_commission	4
1.14.17	With reduced ascorbate as one donor, and incorpora	enzyme_commission	3
3.1.1.61	Protein-glutamate methylesterase	enzyme_commission	4
4.2.3.n14	2-methylisoborneol synthase	enzyme_commission	4
5.5.1.13	Ent-copalyl diphosphate synthase	enzyme_commission	4
2.5.1.91	All-trans-decaprenyl-diphosphate synthase	enzyme_commission	4
2.5.1.96	4,4'-diapophytoene synthase	enzyme_commission	4
5.5.1	Intramolecular lyases	enzyme_commission	3
4.2.3.47	Beta-farnesene synthase	enzyme_commission	4
4.2.3.6	Trichodiene synthase	enzyme_commission	4
5.5.1.12	Copalyl diphosphate synthase	enzyme_commission	4
4.2.3.61	5-epiaristolochene synthase	enzyme_commission	4
5.5.1.19	Lycopene beta-cyclase	enzyme_commission	4
2.5.1.10	(2E,6E)-farnesyl diphosphate synthase	enzyme_commission	4
4.2.3.15	Myrcene synthase	enzyme_commission	4
5.5	Intramolecular lyases	enzyme_commission	2
2.5.1.1	Dimethylallyltranstransferase	enzyme_commission	4
4.2.3.13	(+)-delta-cadinene synthase	enzyme_commission	4
2.5.1.21	Squalene synthase	enzyme_commission	4
2.5.1.32	Phytoene synthase	enzyme_commission	4
2.5.1.29	Geranylgeranyl diphosphate synthase	enzyme_commission	4
4.1.1.39	Ribulose-bisphosphate carboxylase	enzyme_commission	4
5.3.2	Interconverting keto- and enol- groups	enzyme_commission	3
5.3.2.n1	2,3-diketo-5-methylthiopentyl-1-phosphate enolase	enzyme_commission	4
3.4.24	Metalloendopeptidases	enzyme_commission	3
1.10.2	With a cytochrome as acceptor	enzyme_commission	3
6.3.2.19	Ubiquitin--protein ligase	enzyme_commission	4
6.3.2	Acid--D-amino-acid ligases (peptide synthases)	enzyme_commission	3
2.1.1.185	23S rRNA (guanine(2251)-2'-O)-methyltransferase	enzyme_commission	4
3.4.24.69	Bontoxilysin	enzyme_commission	4
2.7.7.2	FAD synthetase	enzyme_commission	4
2.7.1.26	Riboflavin kinase	enzyme_commission	4
2.7.1.161	CTP-dependent riboflavin kinase	enzyme_commission	4
3.2.2.21	DNA-3-methyladenine glycosylase II	enzyme_commission	4
1.2.1.70	Glutamyl-tRNA reductase	enzyme_commission	4
1.2.1	With NAD(+) or NADP(+) as acceptor	enzyme_commission	3
2.3.1.61	Dihydrolipoyllysine-residue succinyltransferase	enzyme_commission	4
2.3.1.21	Carnitine O-palmitoyltransferase	enzyme_commission	4
4.1.1.71	2-oxoglutarate decarboxylase	enzyme_commission	4
6.3.2.26	N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin	enzyme_commission	4
2.3.1.6	Choline O-acetyltransferase	enzyme_commission	4
2.3.1.12	Dihydrolipoyllysine-residue acetyltransferase	enzyme_commission	4
5.1.1.11	Phenylalanine racemase (ATP-hydrolyzing)	enzyme_commission	4
2.3.1.20	Diacylglycerol O-acyltransferase	enzyme_commission	4
1.2.1.31	L-aminoadipate-semialdehyde dehydrogenase	enzyme_commission	4
2.3.1.7	Carnitine O-acetyltransferase	enzyme_commission	4
2.3.1.28	Chloramphenicol O-acetyltransferase	enzyme_commission	4
2.3.1.168	Dihydrolipoyllysine-residue (2-methylpropanoyl)tra	enzyme_commission	4
2.1.2.10	Aminomethyltransferase	enzyme_commission	4
1.5	Acting on the CH-NH group of donors	enzyme_commission	2
1.5.99	With other acceptors	enzyme_commission	3
2.7.4.16	Thiamine-phosphate kinase	enzyme_commission	4
2.7.9.3	Selenide, water dikinase	enzyme_commission	4
6.3.5.3	Phosphoribosylformylglycinamidine synthase	enzyme_commission	4
6.3.5	Carbon--nitrogen ligases with glutamine as amido-N	enzyme_commission	3
2.7.9	Phosphotransferases with paired acceptors	enzyme_commission	3
2.7.1.49	Hydroxymethylpyrimidine kinase	enzyme_commission	4
3.5.99	In other compounds	enzyme_commission	3
1.3.3.11	Pyrroloquinoline-quinone synthase	enzyme_commission	4
3.5.99.2	Aminopyrimidine aminohydrolase	enzyme_commission	4
1.14.99.3	Heme oxygenase	enzyme_commission	4
2.7.4.7	Phosphomethylpyrimidine kinase	enzyme_commission	4
1.14.99	Miscellaneous (requires further characterization)	enzyme_commission	3
1.14.13	With NADH or NADPH as one donor, and incorporation	enzyme_commission	3
1.14.13.39	Nitric-oxide synthase	enzyme_commission	4
4.2.1.96	4a-hydroxytetrahydrobiopterin dehydratase	enzyme_commission	4
1.1.1.267	1-deoxy-D-xylulose-5-phosphate reductoisomerase	enzyme_commission	4
3.6.3	Acting on acid anhydrides; catalyzing transmembran	enzyme_commission	3
3.6.3.14	H(+)-transporting two-sector ATPase	enzyme_commission	4
5.99.1.3	DNA topoisomerase (ATP-hydrolyzing)	enzyme_commission	4
2.7.7.6	DNA-directed RNA polymerase	enzyme_commission	4
3.4.21.22	Coagulation factor IXa	enzyme_commission	4
3.4.21.6	Coagulation factor Xa	enzyme_commission	4
3.4.21.69	Protein C (activated)	enzyme_commission	4
3.4.21.5	Thrombin	enzyme_commission	4
3.4.21.21	Coagulation factor VIIa	enzyme_commission	4
6.1.1.18	Glutamine--tRNA ligase	enzyme_commission	4
6.1.1.17	Glutamate--tRNA ligase	enzyme_commission	4
5.3.1.4	L-arabinose isomerase	enzyme_commission	4
5.3.1.25	L-fucose isomerase	enzyme_commission	4
2.7.4.6	Nucleoside-diphosphate kinase	enzyme_commission	4
2.7.7.56	tRNA nucleotidyltransferase	enzyme_commission	4
2.7.7.8	Polyribonucleotide nucleotidyltransferase	enzyme_commission	4
3.1.4.37	2',3'-cyclic-nucleotide 3'-phosphodiesterase	enzyme_commission	4
3.4.21.110	C5a peptidase	enzyme_commission	4
3.4.17	Metallocarboxypeptidases	enzyme_commission	3
3.4.17.21	Glutamate carboxypeptidase II	enzyme_commission	4
1.1.1.298	3-hydroxypropionate dehydrogenase (NADP(+))	enzyme_commission	4
1.22	Acting on halogen in donors	enzyme_commission	2
1.7.1.4	Nitrite reductase (NAD(P)H)	enzyme_commission	4
1.8.7.1	Sulfite reductase (ferredoxin)	enzyme_commission	4
1.8.1.2	Sulfite reductase (NADPH)	enzyme_commission	4
1.7.7	With an iron-sulfur protein as acceptor	enzyme_commission	3
1.8.7	With an iron-sulfur protein as acceptor	enzyme_commission	3
1.8.99	With other acceptors	enzyme_commission	3
3.1.26.8	Ribonuclease M5	enzyme_commission	4
3.2.1.25	Beta-mannosidase	enzyme_commission	4
3.2.1.31	Beta-glucuronidase	enzyme_commission	4
3.1.21.4	Type II site-specific deoxyribonuclease	enzyme_commission	4
3.1.11	Exodeoxyribonucleases producing 5'-phosphomonoeste	enzyme_commission	3
3.1.11.5	Exodeoxyribonuclease V	enzyme_commission	4
3.1.21	Endodeoxyribonucleases producing 5'-phosphomonoest	enzyme_commission	3
1.15.1.2	Superoxide reductase	enzyme_commission	4
1.15.1	Acting on superoxide as acceptor	enzyme_commission	3
1.15	Acting on superoxide as acceptor	enzyme_commission	2
2.1.1.63	Methylated-DNA--[protein]-cysteine S-methyltransfe	enzyme_commission	4
1.2.99.2	Carbon-monoxide dehydrogenase (acceptor)	enzyme_commission	4
1.2.99	With other acceptors	enzyme_commission	3
2.3.1.48	Histone acetyltransferase	enzyme_commission	4
2.7.7.n1	Adenosine monophosphate-protein transferase	enzyme_commission	4
1.14.11.2	Procollagen-proline dioxygenase	enzyme_commission	4
1.14.11.7	Procollagen-proline 3-dioxygenase	enzyme_commission	4
2.1.1.43	Histone-lysine N-methyltransferase	enzyme_commission	4
2.4.1.255	Protein O-GlcNAc transferase	enzyme_commission	4
2.7.2.4	Aspartate kinase	enzyme_commission	4
2.7.2.8	Acetylglutamate kinase	enzyme_commission	4
2.3.1.1	Amino-acid N-acetyltransferase	enzyme_commission	4
2.7.2.11	Glutamate 5-kinase	enzyme_commission	4
2.7.4.22	UMP kinase	enzyme_commission	4
2.7.2	Phosphotransferases with a carboxyl group as accep	enzyme_commission	3
2.7.2.2	Carbamate kinase	enzyme_commission	4
1.1.1.3	Homoserine dehydrogenase	enzyme_commission	4
3.6.3.12	Potassium-transporting ATPase	enzyme_commission	4
3.6.3.8	Calcium-transporting ATPase	enzyme_commission	4
3.6.3.5	Zinc-exporting ATPase	enzyme_commission	4
3.6.3.6	Proton-exporting ATPase	enzyme_commission	4
3.6.3.10	Hydrogen/potassium-exchanging ATPase	enzyme_commission	4
3.6.3.1	Phospholipid-translocating ATPase	enzyme_commission	4
3.6.3.4	Copper-exporting ATPase	enzyme_commission	4
3.6.3.n1	Cu(+) exporting ATPase	enzyme_commission	4
3.6.3.9	Sodium/potassium-exchanging ATPase	enzyme_commission	4
3.6.3.3	Cadmium-exporting ATPase	enzyme_commission	4
1.14.11.27	[Histone H3]-lysine-36 demethylase	enzyme_commission	4
3.5.1.89	N-acetylglucosaminylphosphatidylinositol deacetyla	enzyme_commission	4
3.5.1.103	deacetylase	enzyme_commission	4
3.2.1.10	Oligo-1,6-glucosidase	enzyme_commission	4
3.2.1.55	Alpha-N-arabinofuranosidase	enzyme_commission	4
3.2.1.84	Glucan 1,3-alpha-glucosidase	enzyme_commission	4
3.2.1.45	Glucosylceramidase	enzyme_commission	4
3.2.1.22	Alpha-galactosidase	enzyme_commission	4
6.3.2.8	UDP-N-acetylmuramate--L-alanine ligase	enzyme_commission	4
6.3.2.13	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-dia	enzyme_commission	4
6.3.2.7	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysin	enzyme_commission	4
6.3.2.17	Tetrahydrofolate synthase	enzyme_commission	4
6.3.2.9	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	enzyme_commission	4
6.3.2.10	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanin	enzyme_commission	4
3.4.21.53	Endopeptidase La	enzyme_commission	4
2.7.1.78	Polynucleotide 5'-hydroxyl-kinase	enzyme_commission	4
2.7.1.22	Ribosylnicotinamide kinase	enzyme_commission	4
2.7.1.130	Tetraacyldisaccharide 4'-kinase	enzyme_commission	4
2.7.1.19	Phosphoribulokinase	enzyme_commission	4
6.6	Forming nitrogen-metal bonds	enzyme_commission	2
6.3.4.2	CTP synthase	enzyme_commission	4
6.3.4.4	Adenylosuccinate synthase	enzyme_commission	4
1.14.11.6	Thymine dioxygenase	enzyme_commission	4
3.1.3.46	Fructose-2,6-bisphosphate 2-phosphatase	enzyme_commission	4
2.8	Transferring sulfur-containing groups	enzyme_commission	2
2.7.4.3	Adenylate kinase	enzyme_commission	4
2.3.1.8	Phosphate acetyltransferase	enzyme_commission	4
6.3.3.3	Dethiobiotin synthase	enzyme_commission	4
2.7.7.4	Sulfate adenylyltransferase	enzyme_commission	4
2.7.1.n4	Nicotinate riboside kinase	enzyme_commission	4
2.7.4.8	Guanylate kinase	enzyme_commission	4
2.5.1.75	tRNA dimethylallyltransferase	enzyme_commission	4
2.7.4.9	dTMP kinase	enzyme_commission	4
3.1.21.3	Type I site-specific deoxyribonuclease	enzyme_commission	4
3.6.1.3	Adenosinetriphosphatase	enzyme_commission	4
1.18.6	With dinitrogen as acceptor	enzyme_commission	3
2.3.1.193	tRNA(Met) cytidine acetyltransferase	enzyme_commission	4
6.3.4.3	Formate--tetrahydrofolate ligase	enzyme_commission	4
2.8.2	Sulfotransferases	enzyme_commission	3
2.7.1.25	Adenylyl-sulfate kinase	enzyme_commission	4
2.7.4.25	(d)CMP kinase	enzyme_commission	4
2.7.1.24	Dephospho-CoA kinase	enzyme_commission	4
2.7.1.48	Uridine kinase	enzyme_commission	4
1.18	Acting on iron-sulfur proteins as donors	enzyme_commission	2
2.7.1.105	6-phosphofructo-2-kinase	enzyme_commission	4
3.5.4.27	Methenyltetrahydromethanopterin cyclohydrolase	enzyme_commission	4
3.2.1.14	Chitinase	enzyme_commission	4
6.1.1.7	Alanine--tRNA ligase	enzyme_commission	4
6.1.1.3	Threonine--tRNA ligase	enzyme_commission	4
1.1.1.130	3-dehydro-L-gulonate 2-dehydrogenase	enzyme_commission	4
3.4.21.73	U-plasminogen activator	enzyme_commission	4
3.4.24.35	Gelatinase B	enzyme_commission	4
3.4.21.38	Coagulation factor XIIa	enzyme_commission	4
3.4.24.24	Gelatinase A	enzyme_commission	4
3.4.21.7	Plasmin	enzyme_commission	4
4.2.1.104	Cyanase	enzyme_commission	4
4.1.3.40	Chorismate lyase	enzyme_commission	4
4.1.3	Oxo-acid-lyases	enzyme_commission	3
2.3.3	Acyl groups converted into alkyl on transfer	enzyme_commission	3
2.3.3.9	Malate synthase	enzyme_commission	4
3.1.11.6	Exodeoxyribonuclease VII	enzyme_commission	4
3.1.3.86	Phosphatidylinositol-3,4,5-trisphosphate 5-phospha	enzyme_commission	4
2.7.8.27	Sphingomyelin synthase	enzyme_commission	4
3.5.1.38	Glutamin-(asparagin-)ase	enzyme_commission	4
3.5.1.1	Asparaginase	enzyme_commission	4
3.6.5.n1	Elongation factor 4	enzyme_commission	4
1.1.1.23	Histidinol dehydrogenase	enzyme_commission	4
3.6.1.31	Phosphoribosyl-ATP diphosphatase	enzyme_commission	4
3.5.4.19	Phosphoribosyl-AMP cyclohydrolase	enzyme_commission	4
3.1.3.84	ADP-ribose 1''-phosphate phosphatase	enzyme_commission	4
3.4.11.1	Leucyl aminopeptidase	enzyme_commission	4
3.4.11.10	Bacterial leucyl aminopeptidase	enzyme_commission	4
3.4.22.69	SARS coronavirus main proteinase	enzyme_commission	4
3.6.3.49	Channel-conductance-controlling ATPase	enzyme_commission	4
3.6.3.44	Xenobiotic-transporting ATPase	enzyme_commission	4
3.6.3.43	Peptide-transporting ATPase	enzyme_commission	4
3.6.3.42	Beta-glucan-transporting ATPase	enzyme_commission	4
4.1.99	Other carbon-carbon lyases	enzyme_commission	3
4.1.99.3	Deoxyribodipyrimidine photo-lyase	enzyme_commission	4
1.1.1.24	Quinate dehydrogenase	enzyme_commission	4
1.4.1	With NAD(+) or NADP(+) as acceptor	enzyme_commission	3
1.1.1.38	Malate dehydrogenase (oxaloacetate-decarboxylating	enzyme_commission	4
1.4.1.3	Glutamate dehydrogenase (NAD(P)(+))	enzyme_commission	4
3.5.4.9	Methenyltetrahydrofolate cyclohydrolase	enzyme_commission	4
1.1.1.40	Malate dehydrogenase (oxaloacetate-decarboxylating	enzyme_commission	4
1.5.1.5	Methylenetetrahydrofolate dehydrogenase (NADP(+))	enzyme_commission	4
1.4.1.4	Glutamate dehydrogenase (NADP(+))	enzyme_commission	4
1.1.1.282	Quinate/shikimate dehydrogenase	enzyme_commission	4
1.5.1	With NAD(+) or NADP(+) as acceptor	enzyme_commission	3
3.2.1.18	Exo-alpha-sialidase	enzyme_commission	4
1.1.1.149	20-alpha-hydroxysteroid dehydrogenase	enzyme_commission	4
1.1.1.263	1,5-anhydro-D-fructose reductase	enzyme_commission	4
1.1.1.2	Alcohol dehydrogenase (NADP(+))	enzyme_commission	4
1.1.1.307	D-xylose reductase	enzyme_commission	4
1.1.1.21	Aldehyde reductase	enzyme_commission	4
1.1.1.274	2,5-didehydrogluconate reductase	enzyme_commission	4
1.1.1.112	Indanol dehydrogenase	enzyme_commission	4
4.3.1	Ammonia-lyases	enzyme_commission	3
1.1.1.95	Phosphoglycerate dehydrogenase	enzyme_commission	4
4.3.1.17	L-serine ammonia-lyase	enzyme_commission	4
2.3.1.182	(R)-citramalate synthase	enzyme_commission	4
2.3.3.13	2-isopropylmalate synthase	enzyme_commission	4
4.2.1.24	Porphobilinogen synthase	enzyme_commission	4
4.2.1.41	5-dehydro-4-deoxyglucarate dehydratase	enzyme_commission	4
2.5.1.55	3-deoxy-8-phosphooctulonate synthase	enzyme_commission	4
4.1.3.39	4-hydroxy-2-oxovalerate aldolase	enzyme_commission	4
4.2.1.52	Dihydrodipicolinate synthase	enzyme_commission	4
4.1.2	Aldehyde-lyases	enzyme_commission	3
4.1.3.3	N-acetylneuraminate lyase	enzyme_commission	4
2.5.1.54	3-deoxy-7-phosphoheptulonate synthase	enzyme_commission	4
4.1.2.4	Deoxyribose-phosphate aldolase	enzyme_commission	4
4.1.2.13	Fructose-bisphosphate aldolase	enzyme_commission	4
3.6.4.6	Vesicle-fusing ATPase	enzyme_commission	4
4.1.1.5	Acetolactate decarboxylase	enzyme_commission	4
5.4.99.18	5-(carboxyamino)imidazole ribonucleotide mutase	enzyme_commission	4
6.3.2.6	Phosphoribosylaminoimidazolesuccinocarboxamide syn	enzyme_commission	4
3.1.4.35	3',5'-cyclic-GMP phosphodiesterase	enzyme_commission	4
5.1.3.24	N-acetylneuraminate epimerase	enzyme_commission	4
1.16.3	With oxygen as acceptor	enzyme_commission	3
1.16	Oxidizing metal ions	enzyme_commission	2
1.4.7	With an iron-sulfur protein as acceptor	enzyme_commission	3
1.2.99.5	Formylmethanofuran dehydrogenase	enzyme_commission	4
1.4.1.14	Glutamate synthase (NADH)	enzyme_commission	4
1.4.9	With a copper protein as acceptor	enzyme_commission	3
2.5.1.16	Spermidine synthase	enzyme_commission	4
2.1.1.216	tRNA (guanine(26)-N(2))-dimethyltransferase	enzyme_commission	4
2.1.1.178	16S rRNA (cytosine(1407)-C(5))-methyltransferase	enzyme_commission	4
2.1.1.173	23S rRNA (guanine(2445)-N(2))-methyltransferase	enzyme_commission	4
2.1.1.163	Demethylmenaquinone methyltransferase	enzyme_commission	4
2.1.1.64	3-demethylubiquinol 3-O-methyltransferase	enzyme_commission	4
2.1.1.223	tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase	enzyme_commission	4
2.5.1.22	Spermine synthase	enzyme_commission	4
2.1.1.170	16S rRNA (guanine(527)-N(7))-methyltransferase	enzyme_commission	4
2.1.1.144	Trans-aconitate 2-methyltransferase	enzyme_commission	4
2.1.1.182	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-d	enzyme_commission	4
2.1.1.166	23S rRNA (uridine(2552)-2'-O-)-methyltransferase	enzyme_commission	4
2.7.7.50	mRNA guanylyltransferase	enzyme_commission	4
2.1.1.191	23S rRNA (cytosine(1962)-C(5))-methyltransferase	enzyme_commission	4
2.1.1.181	23S rRNA (adenine(1618)-N(6))-methyltransferase	enzyme_commission	4
2.1.1.189	23S rRNA (uracil(747)-C(5))-methyltransferase	enzyme_commission	4
2.1.1.37	DNA (cytosine-5-)-methyltransferase	enzyme_commission	4
2.1.1.186	23S rRNA (cytidine(2498)-2'-O)-methyltransferase	enzyme_commission	4
2.1.1.197	Malonyl-CoA O-methyltransferase	enzyme_commission	4
2.1.1.199	16S rRNA (cytosine(1402)-N(4))-methyltransferase	enzyme_commission	4
2.1.1.72	Site-specific DNA-methyltransferase (adenine-speci	enzyme_commission	4
2.1.1.35	tRNA (uracil(54)-C(5))-methyltransferase	enzyme_commission	4
2.1.1.125	Histone-arginine N-methyltransferase	enzyme_commission	4
2.1.1.77	Protein-L-isoaspartate(D-aspartate) O-methyltransf	enzyme_commission	4
2.1.1.222	2-polyprenyl-6-hydroxyphenyl methylase	enzyme_commission	4
2.1.1.172	16S rRNA (guanine(1207)-N(2))-methyltransferase	enzyme_commission	4
2.1.1.174	23S rRNA (guanine(1835)-N(2))-methyltransferase	enzyme_commission	4
2.5.1.43	Nicotianamine synthase	enzyme_commission	4
2.1.1.190	23S rRNA (uracil(1939)-C(5))-methyltransferase	enzyme_commission	4
2.1.1.67	Thiopurine S-methyltransferase	enzyme_commission	4
2.1.1.33	tRNA (guanine(46)-N(7))-methyltransferase	enzyme_commission	4
2.1.1.201	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase	enzyme_commission	4
2.1.1.176	16S rRNA (cytosine(967)-C(5))-methyltransferase	enzyme_commission	4
1.15.1.1	Superoxide dismutase	enzyme_commission	4
3.1.1.32	Phospholipase A(1)	enzyme_commission	4
3.1.1.4	Phospholipase A(2)	enzyme_commission	4
2.5.1.72	Quinolinate synthase	enzyme_commission	4
6.2.1.5	Succinate--CoA ligase (ADP-forming)	enzyme_commission	4
2.3.3.8	ATP citrate synthase	enzyme_commission	4
3.1.3.67	Phosphatidylinositol-3,4,5-trisphosphate 3-phospha	enzyme_commission	4
2.7.8.28	2-phospho-L-lactate transferase	enzyme_commission	4
2.5.1.3	Thiamine-phosphate diphosphorylase	enzyme_commission	4
3.1.27.5	Pancreatic ribonuclease	enzyme_commission	4
3.4.14	Dipeptidyl-peptidases and tripeptidyl-peptidases	enzyme_commission	3
3.4.14.11	Xaa-Pro dipeptidyl-peptidase	enzyme_commission	4
2.8.1.9	Molybdenum cofactor sulfurtransferase	enzyme_commission	4
2.8.1	Sulfurtransferases	enzyme_commission	3
3.4.13.22	D-Ala-D-Ala dipeptidase	enzyme_commission	4
5.3.1.26	Galactose-6-phosphate isomerase	enzyme_commission	4
4.2.3.5	Chorismate synthase	enzyme_commission	4
2.3.1.54	Formate C-acetyltransferase	enzyme_commission	4
6.1.1.20	Phenylalanine--tRNA ligase	enzyme_commission	4
2.8.1.4	tRNA sulfurtransferase	enzyme_commission	4
1.4.3.5	Pyridoxal 5'-phosphate synthase	enzyme_commission	4
1.5.1.42	FMN reductase (NADH)	enzyme_commission	4
1.5.1.36	Flavin reductase (NADH)	enzyme_commission	4
3.4.24.40	Serralysin	enzyme_commission	4
4.3.2.3	Ureidoglycolate lyase	enzyme_commission	4
4.2.1.80	2-oxopent-4-enoate hydratase	enzyme_commission	4
3.7.1.2	Fumarylacetoacetase	enzyme_commission	4
3.7.1.5	Acylpyruvate hydrolase	enzyme_commission	4
3.4.22.56	Caspase-3	enzyme_commission	4
1.2.3	With oxygen as acceptor	enzyme_commission	3
1.18.1	With NAD(+) or NADP(+) as acceptor	enzyme_commission	3
1.17.3	With oxygen as acceptor	enzyme_commission	3
1.2.1.2	Formate dehydrogenase	enzyme_commission	4
1.18.1.3	Ferredoxin--NAD(+) reductase	enzyme_commission	4
1.17.1	With NAD(+) or NADP(+) as acceptor	enzyme_commission	3
4.99.1	Sole sub-subclass for lyases that do not belong in	enzyme_commission	3
4.99.1.2	Alkylmercury lyase	enzyme_commission	4
4.99	Other lyases	enzyme_commission	2
3.1.11.2	Exodeoxyribonuclease III	enzyme_commission	4
3.1.22	Endodeoxyribonucleases producing other than 5'-pho	enzyme_commission	3
3.1.11.1	Exodeoxyribonuclease I	enzyme_commission	4
6.5.1.3	RNA ligase (ATP)	enzyme_commission	4
4.2.1.12	Phosphogluconate dehydratase	enzyme_commission	4
4.2.1.9	Dihydroxy-acid dehydratase	enzyme_commission	4
1.13.12.16	Nitronate monooxygenase	enzyme_commission	4
1.1.1.205	IMP dehydrogenase	enzyme_commission	4
1.7.1.7	GMP reductase	enzyme_commission	4
1.13.12	With incorporation of one atom of oxygen	enzyme_commission	3
3.5.3.4	Allantoicase	enzyme_commission	4
3.4.21.94	Proprotein convertase 2	enzyme_commission	4
3.4.21.75	Furin	enzyme_commission	4
3.4.21.93	Proprotein convertase 1	enzyme_commission	4
3.5.1.52	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagin	enzyme_commission	4
2.5.1.60	Protein geranylgeranyltransferase type II	enzyme_commission	4
4.2.1.3	Aconitate hydratase	enzyme_commission	4
4.2.1.36	Homoaconitate hydratase	enzyme_commission	4
4.2.1.33	3-isopropylmalate dehydratase	enzyme_commission	4
4.2.1.99	2-methylisocitrate dehydratase	enzyme_commission	4
2.10	Transferring molybdenum- or tungsten-containing gr	enzyme_commission	2
2.7.7.75	Molybdopterin adenylyltransferase	enzyme_commission	4
4.99.1.1	Ferrochelatase	enzyme_commission	4
3.6.1.26	CDP-diacylglycerol diphosphatase	enzyme_commission	4
2.7.7.12	UDP-glucose--hexose-1-phosphate uridylyltransferas	enzyme_commission	4
3.6.1.29	Bis(5'-adenosyl)-triphosphatase	enzyme_commission	4
3.3	Acting on ether bonds	enzyme_commission	2
3.3.2	Ether hydrolases	enzyme_commission	3
3.4.11.2	Membrane alanyl aminopeptidase	enzyme_commission	4
3.3.2.6	Leukotriene-A(4) hydrolase	enzyme_commission	4
3.4.11.7	Glutamyl aminopeptidase	enzyme_commission	4
1.10.3.9	Photosystem II	enzyme_commission	4
1.2.1.11	Aspartate-semialdehyde dehydrogenase	enzyme_commission	4
1.3.1.26	Dihydrodipicolinate reductase	enzyme_commission	4
1.2.1.13	Glyceraldehyde-3-phosphate dehydrogenase (NADP(+))	enzyme_commission	4
1.1.1.18	Inositol 2-dehydrogenase	enzyme_commission	4
1.1.1.n6	D-chiro-inositol 3-dehydrogenase	enzyme_commission	4
1.4.1.21	Aspartate dehydrogenase	enzyme_commission	4
1.5.1.9	Saccharopine dehydrogenase (NAD(+), L-glutamate-fo	enzyme_commission	4
1.2.1.72	Erythrose-4-phosphate dehydrogenase	enzyme_commission	4
1.2.1.38	N-acetyl-gamma-glutamyl-phosphate reductase	enzyme_commission	4
1.2.1.10	Acetaldehyde dehydrogenase (acetylating)	enzyme_commission	4
1.1.1.179	D-xylose 1-dehydrogenase (NADP(+))	enzyme_commission	4
1.5.1.8	Saccharopine dehydrogenase (NADP(+), L-lysine-form	enzyme_commission	4
1.2.1.12	Glyceraldehyde-3-phosphate dehydrogenase (phosphor	enzyme_commission	4
5.5.1.4	Inositol-3-phosphate synthase	enzyme_commission	4
1.1.1.49	Glucose-6-phosphate dehydrogenase	enzyme_commission	4
1.2.1.59	Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+	enzyme_commission	4
4.2.1.1	Carbonate dehydratase	enzyme_commission	4
1.8.7.2	Ferredoxin:thioredoxin reductase	enzyme_commission	4
4.1.1.48	Indole-3-glycerol-phosphate synthase	enzyme_commission	4
6.3.5.2	GMP synthase (glutamine-hydrolyzing)	enzyme_commission	4
4.1.3.27	Anthranilate synthase	enzyme_commission	4
3.4.13.21	Dipeptidase E	enzyme_commission	4
5.3.1.24	Phosphoribosylanthranilate isomerase	enzyme_commission	4
1.11.1.6	Catalase	enzyme_commission	4
3.4.19.9	Gamma-glutamyl hydrolase	enzyme_commission	4
2.6.1.85	Aminodeoxychorismate synthase	enzyme_commission	4
2.6	Transferring nitrogenous groups	enzyme_commission	2
3.4.15	Peptidyl-dipeptidases	enzyme_commission	3
2.3.1.46	Homoserine O-succinyltransferase	enzyme_commission	4
2.6.1	Transaminases (aminotransferases)	enzyme_commission	3
3.4.15.6	Cyanophycinase	enzyme_commission	4
4.2.1.130	D-lactate dehydratase	enzyme_commission	4
3.1.1.11	Pectinesterase	enzyme_commission	4
3.4.22.48	Staphopain	enzyme_commission	4
2.7.4.21	Inositol-hexakisphosphate kinase	enzyme_commission	4
2.7.1.68	1-phosphatidylinositol-4-phosphate 5-kinase	enzyme_commission	4
2.7.1.127	Inositol-trisphosphate 3-kinase	enzyme_commission	4
2.7.1.149	1-phosphatidylinositol-5-phosphate 4-kinase	enzyme_commission	4
2.7.1.150	1-phosphatidylinositol-3-phosphate 5-kinase	enzyme_commission	4
2.7.1.151	Inositol-polyphosphate multikinase	enzyme_commission	4
2.7.7.80	Molybdopterin-synthase adenylyltransferase	enzyme_commission	4
2.8.1.11	Molybdopterin-synthase sulfurtransferase	enzyme_commission	4
2.7.1.134	Inositol-tetrakisphosphate 1-kinase	enzyme_commission	4
2.7.1.159	Inositol-1,3,4-trisphosphate 5/6-kinase	enzyme_commission	4
6.3.2.3	Glutathione synthase	enzyme_commission	4
6.3.2.25	Tubulin--tyrosine ligase	enzyme_commission	4
6.3.2.29	Cyanophycin synthase (L-aspartate-adding)	enzyme_commission	4
2.7.4.24	Diphosphoinositol-pentakisphosphate kinase	enzyme_commission	4
6.3.5.5	Carbamoyl-phosphate synthase (glutamine-hydrolyzin	enzyme_commission	4
2.7.9.2	Pyruvate, water dikinase	enzyme_commission	4
2.7.9.1	Pyruvate, phosphate dikinase	enzyme_commission	4
6.3.2.4	D-alanine--D-alanine ligase	enzyme_commission	4
6.3.2.30	Cyanophycin synthase (L-arginine-adding)	enzyme_commission	4
2.5.1.89	diphosphate specific)	enzyme_commission	4
2.5.1.31	diphosphate specific)	enzyme_commission	4
4.6.1.2	Guanylate cyclase	enzyme_commission	4
3.2.1.24	Alpha-mannosidase	enzyme_commission	4
2.4.99	Transferring other glycosyl groups	enzyme_commission	3
3.5.1.41	Chitin deacetylase	enzyme_commission	4
3.5.1.n3	4-deoxy-4-formamido-L-arabinose-phosphoundecapreno	enzyme_commission	4
3.2.1.114	Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase	enzyme_commission	4
4.1.2.25	Dihydroneopterin aldolase	enzyme_commission	4
3.1.2.4	3-hydroxyisobutyryl-CoA hydrolase	enzyme_commission	4
5.1.2.3	3-hydroxybutyryl-CoA epimerase	enzyme_commission	4
3.4.21.92	Endopeptidase Clp	enzyme_commission	4
5.3.3	Transposing C==C bonds	enzyme_commission	3
4.1.1.n2	Ethylmalonyl-CoA decarboxylase	enzyme_commission	4
1.1.1.35	3-hydroxyacyl-CoA dehydrogenase	enzyme_commission	4
4.1.3.36	1,4-dihydroxy-2-naphthoyl-CoA synthase	enzyme_commission	4
6.4.1.2	Acetyl-CoA carboxylase	enzyme_commission	4
5.3.3.8	Dodecenoyl-CoA isomerase	enzyme_commission	4
4.1.1.41	Methylmalonyl-CoA decarboxylase	enzyme_commission	4
5.1.2	Acting on hydroxy acids and derivatives	enzyme_commission	3
4.2.1.17	Enoyl-CoA hydratase	enzyme_commission	4
3.4.14.5	Dipeptidyl-peptidase IV	enzyme_commission	4
3.4.24.78	GPR endopeptidase	enzyme_commission	4
1.14.19	With oxidation of a pair of donors resulting in th	enzyme_commission	3
1.14.19.2	Acyl-[acyl-carrier-protein] desaturase	enzyme_commission	4
1.14.13.81	Magnesium-protoporphyrin IX monomethyl ester (oxid	enzyme_commission	4
1.1.1.158	UDP-N-acetylmuramate dehydrogenase	enzyme_commission	4
3.4.14.1	Dipeptidyl-peptidase I	enzyme_commission	4
1.6.2	With a heme protein as acceptor	enzyme_commission	3
1.6.2.2	Cytochrome-b5 reductase	enzyme_commission	4
1.8.98	With other, known, acceptors	enzyme_commission	3
1.8.98.2	Sulfiredoxin	enzyme_commission	4
3.4.21.42	Complement subcomponent C1s	enzyme_commission	4
3.4.24.21	Astacin	enzyme_commission	4
3.4.21.41	Complement subcomponent C1r	enzyme_commission	4
3.4.22.46	L-peptidase	enzyme_commission	4
3.4.23.44	Nodavirus endopeptidase	enzyme_commission	4
2.3.1.35	Glutamate N-acetyltransferase	enzyme_commission	4
3.6.1.12	dCTP diphosphatase	enzyme_commission	4
2.7.11.26	[Tau protein] kinase	enzyme_commission	4
1.1.98	With other, known, acceptors	enzyme_commission	3
1.14.14.3	Alkanal monooxygenase (FMN-linked)	enzyme_commission	4
1.5.99.11	5,10-methylenetetrahydromethanopterin reductase	enzyme_commission	4
1.14.14.n1	Pyrimidine monooxygenase	enzyme_commission	4
1.14.14.5	Alkanesulfonate monooxygenase	enzyme_commission	4
5.4.99.23	23S rRNA pseudouridine(1911/1915/1917) synthase	enzyme_commission	4
5.4.99.22	23S rRNA pseudouridine(2605) synthase	enzyme_commission	4
5.4.99.19	16S rRNA pseudouridine(516) synthase	enzyme_commission	4
6.1.1.1	Tyrosine--tRNA ligase	enzyme_commission	4
5.4.99.24	23S rRNA pseudouridine(955/2504/2580) synthase	enzyme_commission	4
1.7.2.2	Nitrite reductase (cytochrome; ammonia-forming)	enzyme_commission	4
4.1.2.17	L-fuculose-phosphate aldolase	enzyme_commission	4
4.2.1.109	Methylthioribulose 1-phosphate dehydratase	enzyme_commission	4
5.1.3.4	L-ribulose-5-phosphate 4-epimerase	enzyme_commission	4
4.1.2.19	Rhamnulose-1-phosphate aldolase	enzyme_commission	4
3.1.3.77	Acireductone synthase	enzyme_commission	4
3.2.1.113	Mannosyl-oligosaccharide 1,2-alpha-mannosidase	enzyme_commission	4
3.1.3.8	3-phytase	enzyme_commission	4
3.1.3.13	Bisphosphoglycerate phosphatase	enzyme_commission	4
5.4.2.4	Bisphosphoglycerate mutase	enzyme_commission	4
1.2.7.5	Aldehyde ferredoxin oxidoreductase	enzyme_commission	4
4.1.1.49	Phosphoenolpyruvate carboxykinase (ATP)	enzyme_commission	4
4.1.1.32	Phosphoenolpyruvate carboxykinase (GTP)	enzyme_commission	4
3.4.16.4	Serine-type D-Ala-D-Ala carboxypeptidase	enzyme_commission	4
3.4.16	Serine-type carboxypeptidases	enzyme_commission	3
3.4.11.19	D-stereospecific aminopeptidase	enzyme_commission	4
2.4.1.129	Peptidoglycan glycosyltransferase	enzyme_commission	4
3.5.1.2	Glutaminase	enzyme_commission	4
3.5.2.6	Beta-lactamase	enzyme_commission	4
3.1.13.4	Poly(A)-specific ribonuclease	enzyme_commission	4
3.4.11.18	Methionyl aminopeptidase	enzyme_commission	4
3.4.21.88	Repressor lexA	enzyme_commission	4
2.1.1.4	Acetylserotonin O-methyltransferase	enzyme_commission	4
2.1.1.68	Caffeate O-methyltransferase	enzyme_commission	4
1.97.1.12	Photosystem I	enzyme_commission	4
3.1.4.12	Sphingomyelin phosphodiesterase	enzyme_commission	4
1.1.2.7	Methanol dehydrogenase (cytochrome c)	enzyme_commission	4
1.1.2	With a cytochrome as acceptor	enzyme_commission	3
3.1.3.36	Phosphoinositide 5-phosphatase	enzyme_commission	4
3.1.3.56	Inositol-polyphosphate 5-phosphatase	enzyme_commission	4
3.1.21.1	Deoxyribonuclease I	enzyme_commission	4
2.7.1.40	Pyruvate kinase	enzyme_commission	4
2.7.1.39	Homoserine kinase	enzyme_commission	4
4.1.1.33	Diphosphomevalonate decarboxylase	enzyme_commission	4
2.7.1.36	Mevalonate kinase	enzyme_commission	4
2.7.1.148	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 	enzyme_commission	4
2.7.1.6	Galactokinase	enzyme_commission	4
2.7.1.154	Phosphatidylinositol-4-phosphate 3-kinase	enzyme_commission	4
3.1.4.4	Phospholipase D	enzyme_commission	4
6.1.1.13	D-alanine--poly(phosphoribitol) ligase	enzyme_commission	4
1.5.1.6	Formyltetrahydrofolate dehydrogenase	enzyme_commission	4
5.5.1.n1	D-ribose pyranase	enzyme_commission	4
5.1.3.n2	L-fucose mutarotase	enzyme_commission	4
1.12.98	With other known acceptors	enzyme_commission	3
1.12.98.2	5,10-methenyltetrahydromethanopterin hydrogenase	enzyme_commission	4
1.1.1.45	L-gulonate 3-dehydrogenase	enzyme_commission	4
1.1.1.94	Glycerol-3-phosphate dehydrogenase (NAD(P)(+))	enzyme_commission	4
1.1.1.86	Ketol-acid reductoisomerase	enzyme_commission	4
1.1.1.67	Mannitol 2-dehydrogenase	enzyme_commission	4
1.1.1.17	Mannitol-1-phosphate 5-dehydrogenase	enzyme_commission	4
1.1.1.31	3-hydroxyisobutyrate dehydrogenase	enzyme_commission	4
1.1.1.58	Tagaturonate reductase	enzyme_commission	4
1.1.1.157	3-hydroxybutyryl-CoA dehydrogenase	enzyme_commission	4
1.1.1.44	Phosphogluconate dehydrogenase (decarboxylating)	enzyme_commission	4
1.5.1.2	Pyrroline-5-carboxylate reductase	enzyme_commission	4
1.3.1.12	Prephenate dehydrogenase	enzyme_commission	4
1.1.1.8	Glycerol-3-phosphate dehydrogenase (NAD(+))	enzyme_commission	4
1.1.1.169	2-dehydropantoate 2-reductase	enzyme_commission	4
6.2.1.12	4-coumarate--CoA ligase	enzyme_commission	4
6.2.1.1	Acetate--CoA ligase	enzyme_commission	4
6.2.1.2	Butyrate--CoA ligase	enzyme_commission	4
6.2.1.3	Long-chain-fatty-acid--CoA ligase	enzyme_commission	4
1.13.12.7	Photinus-luciferin 4-monooxygenase (ATP-hydrolyzin	enzyme_commission	4
6.2.1.26	o-succinylbenzoate--CoA ligase	enzyme_commission	4
1.13.11.54	Acireductone dioxygenase (Fe(2+)-requiring)	enzyme_commission	4
1.13.11.53	Acireductone dioxygenase (Ni(2+)-requiring)	enzyme_commission	4
4.1.1.90	Peptidyl-glutamate 4-carboxylase	enzyme_commission	4
1.13.11.5	Homogentisate 1,2-dioxygenase	enzyme_commission	4
5.3.1.n1	5-deoxy-glucuronate isomerase	enzyme_commission	4
5.3.1.17	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomera	enzyme_commission	4
3.5.3.19	Ureidoglycolate hydrolase	enzyme_commission	4
1.13.11.6	3-hydroxyanthranilate 3,4-dioxygenase	enzyme_commission	4
4.2.1.108	Ectoine synthase	enzyme_commission	4
5.1.3.13	dTDP-4-dehydrorhamnose 3,5-epimerase	enzyme_commission	4
2.8.3	CoA-transferases	enzyme_commission	3
2.8.3.16	Formyl-CoA transferase	enzyme_commission	4
4.1.2.43	3-hexulose-6-phosphate synthase	enzyme_commission	4
4.2.1.19	Imidazoleglycerol-phosphate dehydratase	enzyme_commission	4
3.1.3.15	Histidinol-phosphatase	enzyme_commission	4
5.1.3.n3	L-rhamnose mutarotase	enzyme_commission	4
5.3.3.4	Muconolactone Delta-isomerase	enzyme_commission	4
3.4.19.3	Pyroglutamyl-peptidase I	enzyme_commission	4
1.3.1.2	Dihydropyrimidine dehydrogenase (NADP(+))	enzyme_commission	4
1.5.5	With a quinone or similar compound as acceptor	enzyme_commission	3
1.7.99.4	Nitrate reductase	enzyme_commission	4
1.7.99	With other acceptors	enzyme_commission	3
1.8.98.1	CoB--CoM heterodisulfide reductase	enzyme_commission	4
2.8.1.10	Thiazole synthase	enzyme_commission	4
2.4.2.2	Pyrimidine-nucleoside phosphorylase	enzyme_commission	4
2.7.4.23	Ribose 1,5-bisphosphate phosphokinase	enzyme_commission	4
2.4.2.18	Anthranilate phosphoribosyltransferase	enzyme_commission	4
2.4.2.4	Thymidine phosphorylase	enzyme_commission	4
3.1.3.18	Phosphoglycolate phosphatase	enzyme_commission	4
3.11	Acting on carbon-phosphorus bonds	enzyme_commission	2
2.4.1.15	Alpha,alpha-trehalose-phosphate synthase (UDP-form	enzyme_commission	4
3.1.3.n4	2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate 	enzyme_commission	4
3.11.1	Acting on carbon-phosphorus bonds	enzyme_commission	3
3.1.3.74	Pyridoxal phosphatase	enzyme_commission	4
3.8	Acting on halide bonds	enzyme_commission	2
3.1.3.45	3-deoxy-manno-octulosonate-8-phosphatase	enzyme_commission	4
3.1.3.3	Phosphoserine phosphatase	enzyme_commission	4
3.11.1.1	Phosphonoacetaldehyde hydrolase	enzyme_commission	4
3.6.1.1	Inorganic diphosphatase	enzyme_commission	4
3.1.3.70	Mannosyl-3-phosphoglycerate phosphatase	enzyme_commission	4
3.1.3.32	Polynucleotide 3'-phosphatase	enzyme_commission	4
3.1.3.24	Sucrose-phosphate phosphatase	enzyme_commission	4
3.8.1	In C-halide compounds	enzyme_commission	3
5.4.2.8	Phosphomannomutase	enzyme_commission	4
3.1.3.12	Trehalose-phosphatase	enzyme_commission	4
3.8.1.2	(S)-2-haloacid dehalogenase	enzyme_commission	4
4.2.1.79	2-methylcitrate dehydratase	enzyme_commission	4
2.1.1.198	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	enzyme_commission	4
4.99.1.4	Sirohydrochlorin ferrochelatase	enzyme_commission	4
2.1.1.98	Diphthine synthase	enzyme_commission	4
2.1.1.107	Uroporphyrinogen-III C-methyltransferase	enzyme_commission	4
1.3.1.76	Precorrin-2 dehydrogenase	enzyme_commission	4
2.1.1.133	Precorrin-4 C(11)-methyltransferase	enzyme_commission	4
2.7.1.100	S-methyl-5-thioribose kinase	enzyme_commission	4
2.7.1.82	Ethanolamine kinase	enzyme_commission	4
2.7.12	Dual-specificity kinases (those acting on Ser/Thr 	enzyme_commission	3
2.7.1.153	Phosphatidylinositol-4,5-bisphosphate 3-kinase	enzyme_commission	4
2.7.1.95	Kanamycin kinase	enzyme_commission	4
2.7.1.137	Phosphatidylinositol 3-kinase	enzyme_commission	4
2.7.1.89	Thiamine kinase	enzyme_commission	4
2.7.1.n8	Maltokinase	enzyme_commission	4
2.7.1.32	Choline kinase	enzyme_commission	4
1.5.99.9	Methylenetetrahydromethanopterin dehydrogenase	enzyme_commission	4
1.13.11.1	Catechol 1,2-dioxygenase	enzyme_commission	4
1.13.11.3	Protocatechuate 3,4-dioxygenase	enzyme_commission	4
3.1.6	Sulfuric ester hydrolases	enzyme_commission	3
2.7.8.20	Phosphatidylglycerol--membrane-oligosaccharide gly	enzyme_commission	4
5.4.2.7	Phosphopentomutase	enzyme_commission	4
3.1.3.1	Alkaline phosphatase	enzyme_commission	4
4.4.1	Carbon-sulfur lyases	enzyme_commission	3
5.3.99.3	Prostaglandin-E synthase	enzyme_commission	4
4.4.1.20	Leukotriene-C(4) synthase	enzyme_commission	4
4.4	Carbon-sulfur lyases	enzyme_commission	2
1.3.1.38	Trans-2-enoyl-CoA reductase (NADPH)	enzyme_commission	4
1.1.1.284	S-(hydroxymethyl)glutathione dehydrogenase	enzyme_commission	4
1.1.1.103	L-threonine 3-dehydrogenase	enzyme_commission	4
1.3.1.48	15-oxoprostaglandin 13-oxidase	enzyme_commission	4
1.1.1.14	L-iditol 2-dehydrogenase	enzyme_commission	4
1.1.1.47	Glucose 1-dehydrogenase	enzyme_commission	4
1.1.1.9	D-xylulose reductase	enzyme_commission	4
1.1.1.255	Mannitol dehydrogenase	enzyme_commission	4
1.6.5.5	NADPH:quinone reductase	enzyme_commission	4
1.1.1.1	Alcohol dehydrogenase	enzyme_commission	4
1.3.1.74	2-alkenal reductase	enzyme_commission	4
1.1.1.195	Cinnamyl-alcohol dehydrogenase	enzyme_commission	4
2.1.1.80	Protein-glutamate O-methyltransferase	enzyme_commission	4
4.1.1.36	Phosphopantothenoylcysteine decarboxylase	enzyme_commission	4
6.3.2.5	Phosphopantothenate--cysteine ligase	enzyme_commission	4
1.14.16	With reduced pteridine as one donor, and incorpora	enzyme_commission	3
3.1.2.1	Acetyl-CoA hydrolase	enzyme_commission	4
5.3.1.6	Ribose-5-phosphate isomerase	enzyme_commission	4
3.5.99.6	Glucosamine-6-phosphate deaminase	enzyme_commission	4
6.3.3.2	5-formyltetrahydrofolate cyclo-ligase	enzyme_commission	4
5.3.1.23	S-methyl-5-thioribose-1-phosphate isomerase	enzyme_commission	4
3.1.1.31	6-phosphogluconolactonase	enzyme_commission	4
2.7.7.19	Polynucleotide adenylyltransferase	enzyme_commission	4
2.7.7.52	RNA uridylyltransferase	enzyme_commission	4
2.1.1.229	tRNA (carboxymethyluridine(34)-5-O)-methyltransfer	enzyme_commission	4
3.6.1.22	NAD(+) diphosphatase	enzyme_commission	4
3.4.17.10	Carboxypeptidase E	enzyme_commission	4
3.4.17.22	Metallocarboxypeptidase D	enzyme_commission	4
2.7.7.72	CCA tRNA nucleotidyltransferase	enzyme_commission	4
2.4.2.19	Nicotinate-nucleotide diphosphorylase (carboxylati	enzyme_commission	4
2.4.2.11	Nicotinate phosphoribosyltransferase	enzyme_commission	4
3.5.99.7	1-aminocyclopropane-1-carboxylate deaminase	enzyme_commission	4
4.3.1.18	D-serine ammonia-lyase	enzyme_commission	4
4.2.1.20	Tryptophan synthase	enzyme_commission	4
4.3.1.19	Threonine ammonia-lyase	enzyme_commission	4
2.5.1.76	Cysteate synthase	enzyme_commission	4
4.4.1.15	D-cysteine desulfhydrase	enzyme_commission	4
2.5.1.47	Cysteine synthase	enzyme_commission	4
4.2.3.1	Threonine synthase	enzyme_commission	4
4.2.1.22	Cystathionine beta-synthase	enzyme_commission	4
5.1.1.18	Serine racemase	enzyme_commission	4
1.13.11.16	3-carboxyethylcatechol 2,3-dioxygenase	enzyme_commission	4
3.5.1.4	Amidase	enzyme_commission	4
3.5.1.99	Fatty acid amide hydrolase	enzyme_commission	4
3.2.2.5	NAD(+) nucleosidase	enzyme_commission	4
3.4.24.80	Membrane-type matrix metalloproteinase-1	enzyme_commission	4
3.4.24.17	Stromelysin 1	enzyme_commission	4
3.4.24.7	Interstitial collagenase	enzyme_commission	4
3.2.2.22	rRNA N-glycosylase	enzyme_commission	4
2.1.1.193	16S rRNA (uracil(1498)-N(3))-methyltransferase	enzyme_commission	4
5.4.99.25	tRNA pseudouridine(55) synthase	enzyme_commission	4
3.2.1.106	Mannosyl-oligosaccharide glucosidase	enzyme_commission	4
3.2.1.101	Mannan endo-1,6-alpha-mannosidase	enzyme_commission	4
3.2.1.28	Alpha,alpha-trehalase	enzyme_commission	4
3.2.1.33	Amylo-alpha-1,6-glucosidase	enzyme_commission	4
5.1.3.8	N-acylglucosamine 2-epimerase	enzyme_commission	4
2.3.2.15	Glutathione gamma-glutamylcysteinyltransferase	enzyme_commission	4
3.4.22.39	Adenain	enzyme_commission	4
2.3.1.5	Arylamine N-acetyltransferase	enzyme_commission	4
3.4.22.68	Ulp1 peptidase	enzyme_commission	4
1.5.1.20	Methylenetetrahydrofolate reductase (NAD(P)H)	enzyme_commission	4
1.5.99.8	Proline dehydrogenase	enzyme_commission	4
1.13.11.27	4-hydroxyphenylpyruvate dioxygenase	enzyme_commission	4
4.4.1.5	Lactoylglutathione lyase	enzyme_commission	4
1.13.11.2	Catechol 2,3-dioxygenase	enzyme_commission	4
1.13.11.39	Biphenyl-2,3-diol 1,2-dioxygenase	enzyme_commission	4
2.1.1.228	tRNA (guanine(37)-N(1))-methyltransferase	enzyme_commission	4
2.3.1.16	Acetyl-CoA C-acyltransferase	enzyme_commission	4
2.3.1.95	Trihydroxystilbene synthase	enzyme_commission	4
2.3.1.174	3-oxoadipyl-CoA thiolase	enzyme_commission	4
2.3.1.179	Beta-ketoacyl-acyl-carrier-protein synthase II	enzyme_commission	4
2.3.3.10	Hydroxymethylglutaryl-CoA synthase	enzyme_commission	4
2.3.1.74	Naringenin-chalcone synthase	enzyme_commission	4
2.3.1.180	Beta-ketoacyl-acyl-carrier-protein synthase III	enzyme_commission	4
2.3.1.9	Acetyl-CoA C-acetyltransferase	enzyme_commission	4
2.7.1.29	Glycerone kinase	enzyme_commission	4
3.4.17.23	Angiotensin-converting enzyme 2	enzyme_commission	4
6.3.1	Acid--ammonia (or amide) ligases (amide synthases)	enzyme_commission	3
6.3.1.2	Glutamate--ammonia ligase	enzyme_commission	4
4.1.1.15	Glutamate decarboxylase	enzyme_commission	4
2.4.2.28	S-methyl-5'-thioadenosine phosphorylase	enzyme_commission	4
2.4.2.3	Uridine phosphorylase	enzyme_commission	4
2.4.2.1	Purine-nucleoside phosphorylase	enzyme_commission	4
2.4.2.44	S-methyl-5'-thioinosine phosphorylase	enzyme_commission	4
3.2.2.9	Adenosylhomocysteine nucleosidase	enzyme_commission	4
4.1.2.n4	4-hydroxy-2-oxo-heptane-1,7-dioate aldolase	enzyme_commission	4
4.1.1.3	Oxaloacetate decarboxylase	enzyme_commission	4
4.1.2.20	2-dehydro-3-deoxyglucarate aldolase	enzyme_commission	4
4.1.3.30	Methylisocitrate lyase	enzyme_commission	4
4.1.1.31	Phosphoenolpyruvate carboxylase	enzyme_commission	4
4.1.3.1	Isocitrate lyase	enzyme_commission	4
4.1.2.n3	2-keto-3-deoxy-L-rhamnonate aldolase	enzyme_commission	4
2.1.2.11	3-methyl-2-oxobutanoate hydroxymethyltransferase	enzyme_commission	4
2.3.3.1	Citrate (Si)-synthase	enzyme_commission	4
2.3.3.5	2-methylcitrate synthase	enzyme_commission	4
5.4.99.2	Methylmalonyl-CoA mutase	enzyme_commission	4
5.4.99.1	Methylaspartate mutase	enzyme_commission	4
5.1.1.7	Diaminopimelate epimerase	enzyme_commission	4
2.7.7.31	DNA nucleotidylexotransferase	enzyme_commission	4
2.5.1.61	Hydroxymethylbilane synthase	enzyme_commission	4
4.1.99.12	3,4-dihydroxy-2-butanone-4-phosphate synthase	enzyme_commission	4
3.5.4.25	GTP cyclohydrolase II	enzyme_commission	4
1.1.1.193	5-amino-6-(5-phosphoribosylamino)uracil reductase	enzyme_commission	4
3.5.4.5	Cytidine deaminase	enzyme_commission	4
3.5.4.26	Diaminohydroxyphosphoribosylaminopyrimidine deamin	enzyme_commission	4
3.5.4.10	IMP cyclohydrolase	enzyme_commission	4
3.5.4.12	dCMP deaminase	enzyme_commission	4
2.1.2.3	Phosphoribosylaminoimidazolecarboxamide formyltran	enzyme_commission	4
2.7.1.69	Protein-N(pi)-phosphohistidine--sugar phosphotrans	enzyme_commission	4
1.10.3.1	Catechol oxidase	enzyme_commission	4
5.3.3.12	L-dopachrome isomerase	enzyme_commission	4
3.1.26.3	Ribonuclease III	enzyme_commission	4
3.1.4.50	Glycosylphosphatidylinositol phospholipase D	enzyme_commission	4
2.4.1.109	Dolichyl-phosphate-mannose-protein mannosyltransfe	enzyme_commission	4
4.1.1.50	Adenosylmethionine decarboxylase	enzyme_commission	4
4.1.1.4	Acetoacetate decarboxylase	enzyme_commission	4
3.4.14.10	Tripeptidyl-peptidase II	enzyme_commission	4
3.4.14.9	Tripeptidyl-peptidase I	enzyme_commission	4
3.4.21.62	Subtilisin	enzyme_commission	4
3.4.21.63	Oryzin	enzyme_commission	4
2.7.1.30	Glycerol kinase	enzyme_commission	4
2.7.1.170	Anhydro-N-acetylmuramic acid kinase	enzyme_commission	4
2.7.1.1	Hexokinase	enzyme_commission	4
2.7.1.17	Xylulokinase	enzyme_commission	4
2.7.2.1	Acetate kinase	enzyme_commission	4
2.7.2.15	Propionate kinase	enzyme_commission	4
2.7.1.33	Pantothenate kinase	enzyme_commission	4
2.7.1.2	Glucokinase	enzyme_commission	4
2.7.1.5	Rhamnulokinase	enzyme_commission	4
2.7.1.60	N-acylmannosamine kinase	enzyme_commission	4
2.7.1.59	N-acetylglucosamine kinase	enzyme_commission	4
3.6.1.40	Guanosine-5'-triphosphate,3'-diphosphate diphospha	enzyme_commission	4
2.7.1.16	Ribulokinase	enzyme_commission	4
2.7.2.7	Butyrate kinase	enzyme_commission	4
3.6.1.11	Exopolyphosphatase	enzyme_commission	4
1.11.1.8	Iodide peroxidase	enzyme_commission	4
1.14.99.1	Prostaglandin-endoperoxide synthase	enzyme_commission	4
1.1.1.305	UDP-glucuronic acid oxidase (UDP-4-keto-hexauronic	enzyme_commission	4
2.1.2.9	Methionyl-tRNA formyltransferase	enzyme_commission	4
2.1.2.13	UDP-4-amino-4-deoxy-L-arabinose formyltransferase	enzyme_commission	4
4.4.1.21	S-ribosylhomocysteine lyase	enzyme_commission	4
3.4.24.56	Insulysin	enzyme_commission	4
3.4.24.64	Mitochondrial processing peptidase	enzyme_commission	4
3.4.24.55	Pitrilysin	enzyme_commission	4
2.7.11.30	Receptor protein serine/threonine kinase	enzyme_commission	4
3.2.1.37	Xylan 1,4-beta-xylosidase	enzyme_commission	4
5.3.1.13	Arabinose-5-phosphate isomerase	enzyme_commission	4
1.14.13.90	Zeaxanthin epoxidase	enzyme_commission	4
2.1.1.14	5-methyltetrahydropteroyltriglutamate--homocystein	enzyme_commission	4
4.1.1.37	Uroporphyrinogen decarboxylase	enzyme_commission	4
5.4.99.12	tRNA pseudouridine(38-40) synthase	enzyme_commission	4
3.4.11.21	Aspartyl aminopeptidase	enzyme_commission	4
3.6.1.53	Mn(2+)-dependent ADP-ribose/CDP-alcohol diphosphat	enzyme_commission	4
3.1.4.16	2',3'-cyclic-nucleotide 2'-phosphodiesterase	enzyme_commission	4
3.6.1.16	CDP-glycerol diphosphatase	enzyme_commission	4
3.6.1.17	Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)	enzyme_commission	4
3.1.4.17	3',5'-cyclic-nucleotide phosphodiesterase	enzyme_commission	4
3.6.1.41	Bis(5'-nucleosyl)-tetraphosphatase (symmetrical)	enzyme_commission	4
3.6.1.10	Endopolyphosphatase	enzyme_commission	4
3.6.1.54	UDP-2,3-diacylglucosamine diphosphatase	enzyme_commission	4
2.4.2.17	ATP phosphoribosyltransferase	enzyme_commission	4
3.5.1.26	N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	enzyme_commission	4
2.6.1.16	Glutamine--fructose-6-phosphate transaminase (isom	enzyme_commission	4
3.5.1.11	Penicillin amidase	enzyme_commission	4
6.3.5.4	Asparagine synthase (glutamine-hydrolyzing)	enzyme_commission	4
3.4.19.13	Glutathione hydrolase	enzyme_commission	4
3.4.25	Threonine endopeptidases	enzyme_commission	3
3.5.1.97	Acyl-homoserine-lactone acylase	enzyme_commission	4
2.4.2.14	Amidophosphoribosyltransferase	enzyme_commission	4
2.3.2.2	Gamma-glutamyltransferase	enzyme_commission	4
3.4.19.5	Beta-aspartyl-peptidase	enzyme_commission	4
1.14.13.70	Sterol 14-demethylase	enzyme_commission	4
5.3.99.5	Thromboxane-A synthase	enzyme_commission	4
1.1.1.314	Germacrene A alcohol dehydrogenase	enzyme_commission	4
1.14.13.11	Trans-cinnamate 4-monooxygenase	enzyme_commission	4
1.14.99.10	Steroid 21-monooxygenase	enzyme_commission	4
1.14.99.9	Steroid 17-alpha-monooxygenase	enzyme_commission	4
4.2.1.92	Hydroperoxide dehydratase	enzyme_commission	4
1.14.15	With a reduced iron-sulfur protein as one donor, a	enzyme_commission	3
1.14.14.1	Unspecific monooxygenase	enzyme_commission	4
2.7.8.7	Holo-[acyl-carrier-protein] synthase	enzyme_commission	4
3.2.1.143	Poly(ADP-ribose) glycohydrolase	enzyme_commission	4
3.2.2.19	[Protein ADP-ribosylarginine] hydrolase	enzyme_commission	4
4.2.3.12	6-pyruvoyltetrahydropterin synthase	enzyme_commission	4
1.7.1.13	PreQ(1) synthase	enzyme_commission	4
1.7.3.3	Factor independent urate hydroxylase	enzyme_commission	4
3.5.4.16	GTP cyclohydrolase I	enzyme_commission	4
1.7.3	With oxygen as acceptor	enzyme_commission	3
3.1.1.53	Sialate O-acetylesterase	enzyme_commission	4
3.1.1.47	1-alkyl-2-acetylglycerophosphocholine esterase	enzyme_commission	4
5.5.1.6	Chalcone isomerase	enzyme_commission	4
6.1.1.21	Histidine--tRNA ligase	enzyme_commission	4
3.1.3.5	5'-nucleotidase	enzyme_commission	4
3.1.3.6	3'-nucleotidase	enzyme_commission	4
3.6.1.45	UDP-sugar diphosphatase	enzyme_commission	4
2.4.2.29	tRNA-guanine transglycosylase	enzyme_commission	4
3.4.17.1	Carboxypeptidase A	enzyme_commission	4
2.7.1.4	Fructokinase	enzyme_commission	4
2.7.1.146	ADP-specific phosphofructokinase	enzyme_commission	4
2.7.1.35	Pyridoxal kinase	enzyme_commission	4
2.7.1.56	1-phosphofructokinase	enzyme_commission	4
2.7.1.15	Ribokinase	enzyme_commission	4
2.7.1.147	ADP-specific glucokinase	enzyme_commission	4
2.7.1.50	Hydroxyethylthiazole kinase	enzyme_commission	4
2.7.1.20	Adenosine kinase	enzyme_commission	4
2.7.1.144	Tagatose-6-phosphate kinase	enzyme_commission	4
2.7.1.92	5-dehydro-2-deoxygluconokinase	enzyme_commission	4
4.2.1.93	ATP-dependent NAD(P)H-hydrate dehydratase	enzyme_commission	4
3.1.3.66	Phosphatidylinositol-3,4-bisphosphate 4-phosphatas	enzyme_commission	4
1.13.11.11	Tryptophan 2,3-dioxygenase	enzyme_commission	4
3.1.7	Diphosphoric monoester hydrolases	enzyme_commission	3
2.7.6.5	GTP diphosphokinase	enzyme_commission	4
6.1.1.14	Glycine--tRNA ligase	enzyme_commission	4
3.1.7.2	Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase	enzyme_commission	4
1.13.99	Miscellaneous (requires further characterization)	enzyme_commission	3
3.1.5	Triphosphoric monoester hydrolases	enzyme_commission	3
6.1.1.9	Valine--tRNA ligase	enzyme_commission	4
6.1.1.4	Leucine--tRNA ligase	enzyme_commission	4
6.1.1.5	Isoleucine--tRNA ligase	enzyme_commission	4
3.1.13.5	Ribonuclease D	enzyme_commission	4
1.11.1.21	Catalase peroxidase	enzyme_commission	4
4.2.3.3	Methylglyoxal synthase	enzyme_commission	4
3.1.1.29	Aminoacyl-tRNA hydrolase	enzyme_commission	4
3.4.21.43	Classical-complement-pathway C3/C5 convertase	enzyme_commission	4
3.4.21.47	Alternative-complement-pathway C3/C5 convertase	enzyme_commission	4
4.1.1.n1	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline deca	enzyme_commission	4
2.3.1.181	Lipoyl(octanoyl) transferase	enzyme_commission	4
6.1.1.6	Lysine--tRNA ligase	enzyme_commission	4
6.1.1.12	Aspartate--tRNA ligase	enzyme_commission	4
6.1.1.22	Asparagine--tRNA ligase	enzyme_commission	4
2.7.7.63	Lipoate--protein ligase	enzyme_commission	4
6.1.1.15	Proline--tRNA ligase	enzyme_commission	4
6.3.4.15	Biotin--[acetyl-CoA-carboxylase] ligase	enzyme_commission	4
2.3.2.3	Lysyltransferase	enzyme_commission	4
6.1.1.11	Serine--tRNA ligase	enzyme_commission	4
6.3.1.1	Aspartate--ammonia ligase	enzyme_commission	4
2.5.1.59	Protein geranylgeranyltransferase type I	enzyme_commission	4
2.5.1.58	Protein farnesyltransferase	enzyme_commission	4
3.5.1.10	Formyltetrahydrofolate deformylase	enzyme_commission	4
1.21.3	With oxygen as acceptor	enzyme_commission	3
1.21	Acting on x-H and y-H to form an x-y bond	enzyme_commission	2
1.21.3.1	Isopenicillin-N synthase	enzyme_commission	4
1.14.17.4	Aminocyclopropanecarboxylate oxidase	enzyme_commission	4
3.1.1.89	Protein phosphatase methylesterase-1	enzyme_commission	4
3.8.1.5	Haloalkane dehalogenase	enzyme_commission	4
3.1.2.22	Palmitoyl-protein hydrolase	enzyme_commission	4
3.3.2.10	Soluble epoxide hydrolase	enzyme_commission	4
3.1.2.12	S-formylglutathione hydrolase	enzyme_commission	4
3.1.1.22	Hydroxybutyrate-dimer hydrolase	enzyme_commission	4
3.1.1.23	Acylglycerol lipase	enzyme_commission	4
2.3.1.43	Phosphatidylcholine--sterol O-acyltransferase	enzyme_commission	4
3.1.1.85	Pimelyl-[acyl-carrier protein] methyl ester estera	enzyme_commission	4
3.1.1.72	Acetylxylan esterase	enzyme_commission	4
3.4.11.5	Prolyl aminopeptidase	enzyme_commission	4
3.1.2.2	Palmitoyl-CoA hydrolase	enzyme_commission	4
3.4.19.1	Acylaminoacyl-peptidase	enzyme_commission	4
3.1.1.74	Cutinase	enzyme_commission	4
2.3.1.31	Homoserine O-acetyltransferase	enzyme_commission	4
3.1.1.8	Cholinesterase	enzyme_commission	4
3.1.1.13	Sterol esterase	enzyme_commission	4
3.1.1.73	Feruloyl esterase	enzyme_commission	4
4.2.99.20	2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxyl	enzyme_commission	4
3.7.1.14	2-hydroxy-6-oxonona-2,4-dienedioate hydrolase	enzyme_commission	4
3.4.21.26	Prolyl oligopeptidase	enzyme_commission	4
3.7.1.8	2,6-dioxo-6-phenylhexa-3-enoate hydrolase	enzyme_commission	4
3.1.1.7	Acetylcholinesterase	enzyme_commission	4
3.1.1.1	Carboxylesterase	enzyme_commission	4
3.3.2.9	Microsomal epoxide hydrolase	enzyme_commission	4
3.1.1.45	Carboxymethylenebutenolidase	enzyme_commission	4
1.11.1.10	Chloride peroxidase	enzyme_commission	4
3.4.21.97	Assemblin	enzyme_commission	4
4.2.2.n1	Peptidoglycan lytic exotransglycosylase	enzyme_commission	4
3.2.1.17	Lysozyme	enzyme_commission	4
3.2.1.139	Alpha-glucuronidase	enzyme_commission	4
3.5.1.16	Acetylornithine deacetylase	enzyme_commission	4
3.4.11.4	Tripeptide aminopeptidase	enzyme_commission	4
3.5.1.18	Succinyl-diaminopimelate desuccinylase	enzyme_commission	4
3.5.1.14	Aminoacylase	enzyme_commission	4
3.5.1.47	N-acetyldiaminopimelate deacetylase	enzyme_commission	4
3.4.24.85	S2P endopeptidase	enzyme_commission	4
3.4.21.107	Peptidase Do	enzyme_commission	4
3.4.21.108	HtrA2 peptidase	enzyme_commission	4
3.4.21.102	C-terminal processing peptidase	enzyme_commission	4
3.1.27.1	Ribonuclease T(2)	enzyme_commission	4
1.16.1	With NAD(+) or NADP(+) as acceptor	enzyme_commission	3
1.16.1.1	Mercury(II) reductase	enzyme_commission	4
2.5.1.26	Alkylglycerone-phosphate synthase	enzyme_commission	4
1.1.2.4	D-lactate dehydrogenase (cytochrome)	enzyme_commission	4
1.5.99.12	Cytokinin dehydrogenase	enzyme_commission	4
5.3.1.1	Triose-phosphate isomerase	enzyme_commission	4
4.1.1.11	Aspartate 1-decarboxylase	enzyme_commission	4
1.7.2.3	Trimethylamine-N-oxide reductase (cytochrome c)	enzyme_commission	4
5.5.1.7	Chloromuconate cycloisomerase	enzyme_commission	4
5.5.1.1	Muconate cycloisomerase	enzyme_commission	4
4.2.1.11	Phosphopyruvate hydratase	enzyme_commission	4
4.2.1.6	Galactonate dehydratase	enzyme_commission	4
4.2.1.90	L-rhamnonate dehydratase	enzyme_commission	4
4.2.1.113	o-succinylbenzoate synthase	enzyme_commission	4
3.1.31	Endoribonucleases active with either ribo- or deox	enzyme_commission	3
1.20.4.2	Methylarsonate reductase	enzyme_commission	4
6.4.1.3	Propionyl-CoA carboxylase	enzyme_commission	4
2.4.2.9	Uracil phosphoribosyltransferase	enzyme_commission	4
2.4.2.7	Adenine phosphoribosyltransferase	enzyme_commission	4
2.4.2.22	Xanthine phosphoribosyltransferase	enzyme_commission	4
2.4.2.8	Hypoxanthine phosphoribosyltransferase	enzyme_commission	4
2.4.2.10	Orotate phosphoribosyltransferase	enzyme_commission	4
2.7.6.1	Ribose-phosphate diphosphokinase	enzyme_commission	4
4.2.1.84	Nitrile hydratase	enzyme_commission	4
1.3.3.3	Coproporphyrinogen oxidase	enzyme_commission	4
1.8.1.7	Glutathione-disulfide reductase	enzyme_commission	4
1.6.5.4	Monodehydroascorbate reductase (NADH)	enzyme_commission	4
1.8.1.4	Dihydrolipoyl dehydrogenase	enzyme_commission	4
1.6.1.1	NAD(P)(+) transhydrogenase (B-specific)	enzyme_commission	4
1.8.1.14	CoA-disulfide reductase	enzyme_commission	4
4.1.1.84	D-dopachrome decarboxylase	enzyme_commission	4
5.3.2.1	Phenylpyruvate tautomerase	enzyme_commission	4
4.6.1.1	Adenylate cyclase	enzyme_commission	4
5.4.99.5	Chorismate mutase	enzyme_commission	4
4.2.1.91	Arogenate dehydratase	enzyme_commission	4
4.2.1.51	Prephenate dehydratase	enzyme_commission	4
1.1.1.85	3-isopropylmalate dehydrogenase	enzyme_commission	4
2.3.1.n2	Phosphate acyltransferase	enzyme_commission	4
1.1.1.42	Isocitrate dehydrogenase (NADP(+))	enzyme_commission	4
1.1.1.83	D-malate dehydrogenase (decarboxylating)	enzyme_commission	4
1.1.1.262	4-hydroxythreonine-4-phosphate dehydrogenase	enzyme_commission	4
4.1.1.73	Tartrate decarboxylase	enzyme_commission	4
1.1.1.41	Isocitrate dehydrogenase (NAD(+))	enzyme_commission	4
1.1.1.93	Tartrate dehydrogenase	enzyme_commission	4
3.2.2.8	Ribosylpyrimidine nucleosidase	enzyme_commission	4
3.2.2.3	Uridine nucleosidase	enzyme_commission	4
1.4.1.13	Glutamate synthase (NADPH)	enzyme_commission	4
4.2.1.126	N-acetylmuramic acid 6-phosphate etherase	enzyme_commission	4
5.3.1.9	Glucose-6-phosphate isomerase	enzyme_commission	4
5.3.1.28	D-sedoheptulose 7-phosphate isomerase	enzyme_commission	4
2.8.4	Transferring alkylthio groups	enzyme_commission	3
4.3.1.4	Formimidoyltetrahydrofolate cyclodeaminase	enzyme_commission	4
2.1.2.5	Glutamate formimidoyltransferase	enzyme_commission	4
3.5.1.98	Histone deacetylase	enzyme_commission	4
3.5.3.8	Formimidoylglutamase	enzyme_commission	4
3.5.3.1	Arginase	enzyme_commission	4
3.5.3.11	Agmatinase	enzyme_commission	4
6.3.4.5	Argininosuccinate synthase	enzyme_commission	4
6.3.1.5	NAD(+) synthase	enzyme_commission	4
6.3.4.19	tRNA(Ile)-lysidine synthetase	enzyme_commission	4
1.8.4.8	Phosphoadenylyl-sulfate reductase (thioredoxin)	enzyme_commission	4
1.8.4	With a disulfide as acceptor	enzyme_commission	3
6.3.5.1	NAD(+) synthase (glutamine-hydrolyzing)	enzyme_commission	4
3.6.3.20	Glycerol-3-phosphate-transporting ATPase	enzyme_commission	4
3.6.3.30	Fe(3+)-transporting ATPase	enzyme_commission	4
3.6.3.31	Polyamine-transporting ATPase	enzyme_commission	4
3.6.3.29	Molybdate-transporting ATPase	enzyme_commission	4
3.6.3.19	Maltose-transporting ATPase	enzyme_commission	4
3.6.3.25	Sulfate-transporting ATPase	enzyme_commission	4
2.7.11.21	Polo kinase	enzyme_commission	4
2.3.1.189	Mycothiol synthase	enzyme_commission	4
2.3.2.6	Leucyltransferase	enzyme_commission	4
2.3.1.88	Peptide alpha-N-acetyltransferase	enzyme_commission	4
2.3.1.13	Glycine N-acyltransferase	enzyme_commission	4
2.3.2.8	Arginyltransferase	enzyme_commission	4
2.3.1.87	Aralkylamine N-acetyltransferase	enzyme_commission	4
2.3.1.128	Ribosomal-protein-alanine N-acetyltransferase	enzyme_commission	4
2.3.1.82	Aminoglycoside N(6')-acetyltransferase	enzyme_commission	4
2.3.1.97	Glycylpeptide N-tetradecanoyltransferase	enzyme_commission	4
2.3.1.178	Diaminobutyrate acetyltransferase	enzyme_commission	4
2.3.1.108	Alpha-tubulin N-acetyltransferase	enzyme_commission	4
2.3.1.184	Acyl-homoserine-lactone synthase	enzyme_commission	4
2.3.1.109	Arginine N-succinyltransferase	enzyme_commission	4
2.3.1.17	Aspartate N-acetyltransferase	enzyme_commission	4
2.3.1.183	Phosphinothricin acetyltransferase	enzyme_commission	4
2.3.1.57	Diamine N-acetyltransferase	enzyme_commission	4
2.3.1.4	Glucosamine-phosphate N-acetyltransferase	enzyme_commission	4
1.8.4.11	Peptide-methionine (S)-S-oxide reductase	enzyme_commission	4
1.4.3.22	Diamine oxidase	enzyme_commission	4
1.4.3.21	Primary-amine oxidase	enzyme_commission	4
5.1.1.3	Glutamate racemase	enzyme_commission	4
2.1.1.148	Thymidylate synthase (FAD)	enzyme_commission	4
2.7.7.47	Streptomycin 3''-adenylyltransferase	enzyme_commission	4
3.5.1.96	Succinylglutamate desuccinylase	enzyme_commission	4
2.3.2.5	Glutaminyl-peptide cyclotransferase	enzyme_commission	4
3.4.13.18	Cytosol nonspecific dipeptidase	enzyme_commission	4
3.5.1.15	Aspartoacylase	enzyme_commission	4
3.3.2.1	Isochorismatase	enzyme_commission	4
3.5.1.n4	Peroxyureidoacrylate/ureidoacrylate amidohydrolase	enzyme_commission	4
3.6.1.28	Thiamine-triphosphatase	enzyme_commission	4
3.4.21.89	Signal peptidase I	enzyme_commission	4
3.2.1.8	Endo-1,4-beta-xylanase	enzyme_commission	4
2.8.1.2	3-mercaptopyruvate sulfurtransferase	enzyme_commission	4
2.8.1.1	Thiosulfate sulfurtransferase	enzyme_commission	4
3.1.13.1	Exoribonuclease II	enzyme_commission	4
6.1.1.10	Methionine--tRNA ligase	enzyme_commission	4
3.1.26.12	Ribonuclease E	enzyme_commission	4
4.1.1.22	Histidine decarboxylase	enzyme_commission	4
5.1.3.3	Aldose 1-epimerase	enzyme_commission	4
3.2.1.122	Maltose-6'-phosphate glucosidase	enzyme_commission	4
1.1.1.27	L-lactate dehydrogenase	enzyme_commission	4
1.1.1.37	Malate dehydrogenase	enzyme_commission	4
1.1.1.82	Malate dehydrogenase (NADP(+))	enzyme_commission	4
2.3.2.4	Gamma-glutamylcyclotransferase	enzyme_commission	4
3.4.24.82	ADAMTS-4 endopeptidase	enzyme_commission	4
4.2.1.2	Fumarate hydratase	enzyme_commission	4
4.3.1.24	Phenylalanine ammonia-lyase	enzyme_commission	4
4.3.1.3	Histidine ammonia-lyase	enzyme_commission	4
3.1.3.71	2-phosphosulfolactate phosphatase	enzyme_commission	4
6.3.2.1	Pantoate--beta-alanine ligase	enzyme_commission	4
2.7.7.15	Choline-phosphate cytidylyltransferase	enzyme_commission	4
6.1.1.16	Cysteine--tRNA ligase	enzyme_commission	4
2.7.4.14	UMP/CMP kinase	enzyme_commission	4
2.7.7.18	Nicotinate-nucleotide adenylyltransferase	enzyme_commission	4
6.3.1.13	ligase	enzyme_commission	4
2.7.7.14	Ethanolamine-phosphate cytidylyltransferase	enzyme_commission	4
2.7.7.1	Nicotinamide-nucleotide adenylyltransferase	enzyme_commission	4
6.1.1.19	Arginine--tRNA ligase	enzyme_commission	4
2.7.7.3	Pantetheine-phosphate adenylyltransferase	enzyme_commission	4
5.3.1.22	Hydroxypyruvate isomerase	enzyme_commission	4
5.3.1.14	L-rhamnose isomerase	enzyme_commission	4
5.1.3.22	L-ribulose-5-phosphate 3-epimerase	enzyme_commission	4
4.2.1.44	Myo-inosose-2 dehydratase	enzyme_commission	4
4.2.1.8	Mannonate dehydratase	enzyme_commission	4
5.3.1.5	Xylose isomerase	enzyme_commission	4
3.1.21.2	Deoxyribonuclease IV (phage-T(4)-induced)	enzyme_commission	4
2.7.6.2	Thiamine diphosphokinase	enzyme_commission	4
3.1.26.11	Ribonuclease Z	enzyme_commission	4
1.14.18.2	CMP-N-acetylneuraminate monooxygenase	enzyme_commission	4
3.1.4.54	N-acetylphosphatidylethanolamine-hydrolyzing phosp	enzyme_commission	4
3.1.1.81	Quorum-quenching N-acyl-homoserine lactonase	enzyme_commission	4
3.1.2.6	Hydroxyacylglutathione hydrolase	enzyme_commission	4
2.1.1.45	Thymidylate synthase	enzyme_commission	4
1.5.1.3	Dihydrofolate reductase	enzyme_commission	4
3.4.24.75	Lysostaphin	enzyme_commission	4
1.14.99.29	Deoxyhypusine monooxygenase	enzyme_commission	4
3.3.1	Thioether and trialkylsulfonium hydrolases	enzyme_commission	3
1.1.1.290	4-phosphoerythronate dehydrogenase	enzyme_commission	4
1.1.1.26	Glyoxylate reductase	enzyme_commission	4
1.5.1.7	Saccharopine dehydrogenase (NAD(+), L-lysine-formi	enzyme_commission	4
1.4.1.1	Alanine dehydrogenase	enzyme_commission	4
1.1.1.81	Hydroxypyruvate reductase	enzyme_commission	4
1.1.1.28	D-lactate dehydrogenase	enzyme_commission	4
1.1.1.79	Glyoxylate reductase (NADP(+))	enzyme_commission	4
3.5.2.17	Hydroxyisourate hydrolase	enzyme_commission	4
1.3.1.32	Maleylacetate reductase	enzyme_commission	4
1.1.1.261	sn-glycerol-1-phosphate dehydrogenase	enzyme_commission	4
1.1.1.6	Glycerol dehydrogenase	enzyme_commission	4
1.1.99	With other acceptors	enzyme_commission	3
1.1.99.24	Hydroxyacid-oxoacid transhydrogenase	enzyme_commission	4
3.6.1.52	Diphosphoinositol-polyphosphate diphosphatase	enzyme_commission	4
3.6.1.13	ADP-ribose diphosphatase	enzyme_commission	4
3.6.1.55	8-oxo-dGTP diphosphatase	enzyme_commission	4
5.3.3.2	Isopentenyl-diphosphate Delta-isomerase	enzyme_commission	4
3.1.3.43	[Pyruvate dehydrogenase (acetyl-transferring)]-pho	enzyme_commission	4
3.6.1.43	Dolichyldiphosphatase	enzyme_commission	4
3.1.3.4	Phosphatidate phosphatase	enzyme_commission	4
3.1.3.9	Glucose-6-phosphatase	enzyme_commission	4
2.3.2.17	glycyltransferase	enzyme_commission	4
2.1.1.5	Betaine--homocysteine S-methyltransferase	enzyme_commission	4
2.1.1.10	Homocysteine S-methyltransferase	enzyme_commission	4
2.7.1.86	NADH kinase	enzyme_commission	4
2.7.1.23	NAD(+) kinase	enzyme_commission	4
2.7.1.94	Acylglycerol kinase	enzyme_commission	4
2.7.1.91	Sphinganine kinase	enzyme_commission	4
3.5.4.13	dCTP deaminase	enzyme_commission	4
3.1.27.3	Ribonuclease T(1)	enzyme_commission	4
2.3.1.89	Tetrahydrodipicolinate N-acetyltransferase	enzyme_commission	4
2.3.1.117	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-suc	enzyme_commission	4
2.3.1.30	Serine O-acetyltransferase	enzyme_commission	4
2.3.1.129	Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosami	enzyme_commission	4
2.3.1.191	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltran	enzyme_commission	4
4.2.1.119	Enoyl-CoA hydratase 2	enzyme_commission	4
5.1.3.20	ADP-glyceromanno-heptose 6-epimerase	enzyme_commission	4
4.2.1.46	dTDP-glucose 4,6-dehydratase	enzyme_commission	4
5.3.3.1	Steroid Delta-isomerase	enzyme_commission	4
4.2.1.47	GDP-mannose 4,6-dehydratase	enzyme_commission	4
4.1.1.35	UDP-glucuronate decarboxylase	enzyme_commission	4
4.3.1.12	Ornithine cyclodeaminase	enzyme_commission	4
6.2.1.4	Succinate--CoA ligase (GDP-forming)	enzyme_commission	4
5.1.3.2	UDP-glucose 4-epimerase	enzyme_commission	4
2.1.3	Carboxyl- and carbamoyltransferases	enzyme_commission	3
3.5.2.3	Dihydroorotase	enzyme_commission	4
2.1.3.2	Aspartate carbamoyltransferase	enzyme_commission	4
4.4.1.14	1-aminocyclopropane-1-carboxylate synthase	enzyme_commission	4
2.1.2.1	Glycine hydroxymethyltransferase	enzyme_commission	4
4.1.1.81	Threonine-phosphate decarboxylase	enzyme_commission	4
4.1.1.28	Aromatic-L-amino-acid decarboxylase	enzyme_commission	4
2.5.1.73	O-phospho-L-seryl-tRNA:Cys-tRNA synthase	enzyme_commission	4
2.3.1.47	8-amino-7-oxononanoate synthase	enzyme_commission	4
1.4.4	With a disulfide as acceptor	enzyme_commission	3
2.3.1.37	5-aminolevulinate synthase	enzyme_commission	4
2.5.1.48	Cystathionine gamma-synthase	enzyme_commission	4
2.6.1.9	Histidinol-phosphate transaminase	enzyme_commission	4
4.4.1.16	Selenocysteine lyase	enzyme_commission	4
2.3.1.29	Glycine C-acetyltransferase	enzyme_commission	4
4.1.1.25	Tyrosine decarboxylase	enzyme_commission	4
5.4.3	Transferring amino groups	enzyme_commission	3
4.1.99.1	Tryptophanase	enzyme_commission	4
4.4.1.1	Cystathionine gamma-lyase	enzyme_commission	4
3.7.1.3	Kynureninase	enzyme_commission	4
2.9	Transferring selenium-containing groups	enzyme_commission	2
5.4.3.8	Glutamate-1-semialdehyde 2,1-aminomutase	enzyme_commission	4
4.1.2.48	Low-specificity L-threonine aldolase	enzyme_commission	4
4.4.1.8	Cystathionine beta-lyase	enzyme_commission	4
4.1.2.27	Sphinganine-1-phosphate aldolase	enzyme_commission	4
2.3.1.50	Serine C-palmitoyltransferase	enzyme_commission	4
2.8.1.7	Cysteine desulfurase	enzyme_commission	4
4.4.1.13	Cysteine-S-conjugate beta-lyase	enzyme_commission	4
4.1.99.2	Tyrosine phenol-lyase	enzyme_commission	4
3.5.1.102	deformylase	enzyme_commission	4
3.6.1.19	Nucleoside-triphosphate diphosphatase	enzyme_commission	4
5.3.1.n2	Ribose 1,5-bisphosphate isomerase	enzyme_commission	4
2.1.1.61	tRNA (5-methylaminomethyl-2-thiouridylate)-methylt	enzyme_commission	4
1.4.3.2	L-amino-acid oxidase	enzyme_commission	4
1.14.13.127	3-(3-hydroxy-phenyl)propanoic acid hydroxylase	enzyme_commission	4
1.1.3	With oxygen as acceptor	enzyme_commission	3
1.3.8.2	4,4'-diapophytoene desaturase	enzyme_commission	4
1.14.13.132	Squalene monooxygenase	enzyme_commission	4
2.1.1.74	(FADH(2)-oxidizing)	enzyme_commission	4
1.8.3.5	Prenylcysteine oxidase	enzyme_commission	4
1.3.1.83	Geranylgeranyl diphosphate reductase	enzyme_commission	4
5.2.1.13	Prolycopene isomerase	enzyme_commission	4
1.3.5.6	9,9'-di-cis-zeta-carotene desaturase	enzyme_commission	4
1.1.99.1	Choline dehydrogenase	enzyme_commission	4
1.4.3.4	Monoamine oxidase	enzyme_commission	4
1.14.13.9	Kynurenine 3-monooxygenase	enzyme_commission	4
1.4.99	With other acceptors	enzyme_commission	3
1.13.12.3	Tryptophan 2-monooxygenase	enzyme_commission	4
1.3.3.4	Protoporphyrinogen oxidase	enzyme_commission	4
4.1.2.10	(R)-mandelonitrile lyase	enzyme_commission	4
1.14.99.44	Diapolycopene oxygenase	enzyme_commission	4
1.14.13.8	Flavin-containing monooxygenase	enzyme_commission	4
1.8.1.9	Thioredoxin-disulfide reductase	enzyme_commission	4
1.5.3	With oxygen as acceptor	enzyme_commission	3
3.1.4.52	Cyclic-guanylate-specific phosphodiesterase	enzyme_commission	4
3.1.4.41	Sphingomyelin phosphodiesterase D	enzyme_commission	4
4.6.1.13	Phosphatidylinositol diacylglycerol-lyase	enzyme_commission	4
1.2.1.8	Betaine-aldehyde dehydrogenase	enzyme_commission	4
1.2.1.71	Succinylglutamate-semialdehyde dehydrogenase	enzyme_commission	4
1.2.1.19	Aminobutyraldehyde dehydrogenase	enzyme_commission	4
1.2.1.5	Aldehyde dehydrogenase (NAD(P)(+))	enzyme_commission	4
1.2.1.3	Aldehyde dehydrogenase (NAD(+))	enzyme_commission	4
1.5.1.12	1-pyrroline-5-carboxylate dehydrogenase	enzyme_commission	4
1.2.1.27	Methylmalonate-semialdehyde dehydrogenase (acylati	enzyme_commission	4
1.2.1.41	Glutamate-5-semialdehyde dehydrogenase	enzyme_commission	4
1.2.1.18	Malonate-semialdehyde dehydrogenase (acetylating)	enzyme_commission	4
1.2.1.36	Retinal dehydrogenase	enzyme_commission	4
6.3.2.2	Glutamate--cysteine ligase	enzyme_commission	4
2.7.3.2	Creatine kinase	enzyme_commission	4
3.6.4.3	Microtubule-severing ATPase	enzyme_commission	4
5.1.3.9	N-acylglucosamine-6-phosphate 2-epimerase	enzyme_commission	4
5.1.3.1	Ribulose-phosphate 3-epimerase	enzyme_commission	4
4.1.1.23	Orotidine-5'-phosphate decarboxylase	enzyme_commission	4
5.3.1.16	isomerase	enzyme_commission	4
4.1.1.85	3-dehydro-L-gulonate-6-phosphate decarboxylase	enzyme_commission	4
5.4.99.39	Beta-amyrin synthase	enzyme_commission	4
5.4.99.17	Squalene--hopene cyclase	enzyme_commission	4
5.4.99.8	Cycloartenol synthase	enzyme_commission	4
5.4.99.41	Lupeol synthase	enzyme_commission	4
5.4.99.7	Lanosterol synthase	enzyme_commission	4
4.2.3.19	Ent-kaurene synthase	enzyme_commission	4
4.2.1.129	Squalene--hopanol cyclase	enzyme_commission	4
2.5.1.9	Riboflavin synthase	enzyme_commission	4
1.1.1.34	Hydroxymethylglutaryl-CoA reductase (NADPH)	enzyme_commission	4
3.5.1.44	Protein-glutamine glutaminase	enzyme_commission	4
2.3.1.81	Aminoglycoside N(3')-acetyltransferase	enzyme_commission	4
4.1.3.38	Aminodeoxychorismate lyase	enzyme_commission	4
2.6.1.42	Branched-chain-amino-acid transaminase	enzyme_commission	4
2.6.1.21	D-amino-acid transaminase	enzyme_commission	4
3.6.1.7	Acylphosphatase	enzyme_commission	4
4.2.2.3	Poly(beta-D-mannuronate) lyase	enzyme_commission	4
2.1.1.192	23S rRNA (adenine(2503)-C(2))-methyltransferase	enzyme_commission	4
1.97.1.4	[Formate-C-acetyltransferase]-activating enzyme	enzyme_commission	4
1.3.99.22	Coproporphyrinogen dehydrogenase	enzyme_commission	4
2.5.1.77	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthas	enzyme_commission	4
2.6.1.62	Adenosylmethionine--8-amino-7-oxononanoate transam	enzyme_commission	4
2.8.1.8	Lipoyl synthase	enzyme_commission	4
2.1.1.224	23S rRNA (adenine(2503)-C(8))-methyltransferase	enzyme_commission	4
2.8.1.6	Biotin synthase	enzyme_commission	4
3.2.1.153	Fructan beta-(2,1)-fructosidase	enzyme_commission	4
3.2.1.99	Arabinan endo-1,5-alpha-L-arabinosidase	enzyme_commission	4
2.4.1.10	Levansucrase	enzyme_commission	4
3.2.1.26	Beta-fructofuranosidase	enzyme_commission	4
4.2.1.60	3-hydroxydecanoyl-[acyl-carrier-protein] dehydrata	enzyme_commission	4
3.1.2.28	1,4-dihydroxy-2-naphthoyl-CoA hydrolase	enzyme_commission	4
3.5.1.3	Omega-amidase	enzyme_commission	4
3.5.1.12	Biotinidase	enzyme_commission	4
3.5.1.49	Formamidase	enzyme_commission	4
3.5.1.6	Beta-ureidopropionase	enzyme_commission	4
3.5.5	In nitriles	enzyme_commission	3
3.5.1.92	Pantetheine hydrolase	enzyme_commission	4
1.8.1.12	Trypanothione-disulfide reductase	enzyme_commission	4
1.4.3.1	D-aspartate oxidase	enzyme_commission	4
1.4.3.3	D-amino-acid oxidase	enzyme_commission	4
1.18.1.2	Ferredoxin--NADP(+) reductase	enzyme_commission	4
1.6.5.2	NAD(P)H dehydrogenase (quinone)	enzyme_commission	4
1.5.1.38	FMN reductase (NADPH)	enzyme_commission	4
1.6.2.4	NADPH--hemoprotein reductase	enzyme_commission	4
1.16.1.8	[Methionine synthase] reductase	enzyme_commission	4
3.5.3.6	Arginine deiminase	enzyme_commission	4
3.5.3.23	N-succinylarginine dihydrolase	enzyme_commission	4
3.5.3.12	Agmatine deiminase	enzyme_commission	4
2.1.4	Amidinotransferases	enzyme_commission	3
1.14.15.7	Choline monooxygenase	enzyme_commission	4
2.7.4.10	Nucleoside-triphosphate--adenylate kinase	enzyme_commission	4
1.1.3.37	D-arabinono-1,4-lactone oxidase	enzyme_commission	4
1.3.1.72	Delta(24)-sterol reductase	enzyme_commission	4
1.1.3.10	Pyranose oxidase	enzyme_commission	4
1.14.13.24	3-hydroxybenzoate 6-monooxygenase	enzyme_commission	4
2.8.1.12	Molybdopterin synthase	enzyme_commission	4
3.2.2.28	Double-stranded uracil-DNA glycosylase	enzyme_commission	4
3.2.2.27	Uracil-DNA glycosylase	enzyme_commission	4
1.3.5.2	Dihydroorotate dehydrogenase (quinone)	enzyme_commission	4
1.6.99.1	NADPH dehydrogenase	enzyme_commission	4
2.5.1.41	Phosphoglycerol geranylgeranyltransferase	enzyme_commission	4
1.3.1.89	tRNA-dihydrouridine(47) synthase (NAD(P)(+))	enzyme_commission	4
1.3.1.14	Dihydroorotate dehydrogenase (NAD(+))	enzyme_commission	4
1.3.1.42	12-oxophytodienoate reductase	enzyme_commission	4
1.1.3.15	(S)-2-hydroxy-acid oxidase	enzyme_commission	4
1.1.2.3	L-lactate dehydrogenase (cytochrome)	enzyme_commission	4
1.3.98	With other, known, acceptors	enzyme_commission	3
5.4.4.2	Isochorismate synthase	enzyme_commission	4
5.4.4	Transferring hydroxy groups	enzyme_commission	3
3.1.1.2	Arylesterase	enzyme_commission	4
4.3.3	Amine-lyases	enzyme_commission	3
3.1.1.17	Gluconolactonase	enzyme_commission	4
3.1.8	Phosphoric triester hydrolases	enzyme_commission	3
2.6.99	Transferring other nitrogenous groups	enzyme_commission	3
3.2.1.73	Licheninase	enzyme_commission	4
3.2.1.6	Endo-1,3(4)-beta-glucanase	enzyme_commission	4
2.4.1.207	Xyloglucan:xyloglucosyl transferase	enzyme_commission	4
3.2.1.151	Xyloglucan-specific endo-beta-1,4-glucanase	enzyme_commission	4
2.7.8.5	CDP-diacylglycerol--glycerol-3-phosphate 3-phospha	enzyme_commission	4
3.4.21.72	IgA-specific serine endopeptidase	enzyme_commission	4
3.4.24.81	ADAM10 endopeptidase	enzyme_commission	4
1.10.9	With a copper protein as acceptor	enzyme_commission	3
4.2.2.10	Pectin lyase	enzyme_commission	4
4.2.2.2	Pectate lyase	enzyme_commission	4
3.2.1.15	Polygalacturonase	enzyme_commission	4
3.2.1.67	Galacturan 1,4-alpha-galacturonidase	enzyme_commission	4
3.2.1.n1	Blood group B branched chain alpha-1,3-galactosida	enzyme_commission	4
3.2.1.171	Rhamnogalacturonan hydrolase	enzyme_commission	4
3.2.1.n2	Blood group B linear chain alpha-1,3-galactosidase	enzyme_commission	4
2.7.1.90	Diphosphate--fructose-6-phosphate 1-phosphotransfe	enzyme_commission	4
2.7.1.11	6-phosphofructokinase	enzyme_commission	4
2.1.1.200	tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransfe	enzyme_commission	4
2.1.1.207	tRNA (cytidine(34)-2'-O)-methyltransferase	enzyme_commission	4
2.1.1.177	23S rRNA (pseudouridine(1915)-N(3))-methyltransfer	enzyme_commission	4
2.1.1.206	tRNA (cytidine(56)-2'-O)-methyltransferase	enzyme_commission	4
2.7.11.16	[G-protein-coupled receptor] kinase	enzyme_commission	4
2.7.11.14	Rhodopsin kinase	enzyme_commission	4
3.4.21.19	Glutamyl endopeptidase	enzyme_commission	4
3.4.21.10	Acrosin	enzyme_commission	4
3.4.21.74	Venombin A	enzyme_commission	4
3.4.21.59	Tryptase	enzyme_commission	4
3.4.21.4	Trypsin	enzyme_commission	4
3.4.21.36	Pancreatic elastase	enzyme_commission	4
3.4.21.1	Chymotrypsin	enzyme_commission	4
3.4.21.39	Chymase	enzyme_commission	4
3.4.21.35	Tissue kallikrein	enzyme_commission	4
3.4.13.19	Membrane dipeptidase	enzyme_commission	4
5.3.1.12	Glucuronate isomerase	enzyme_commission	4
3.5.4.6	AMP deaminase	enzyme_commission	4
4.1.1.45	Aminocarboxymuconate-semialdehyde decarboxylase	enzyme_commission	4
3.5.4.4	Adenosine deaminase	enzyme_commission	4
1.8.4.12	Peptide-methionine (R)-S-oxide reductase	enzyme_commission	4
4.4.1.22	S-(hydroxymethyl)glutathione synthase	enzyme_commission	4
2.7.2.3	Phosphoglycerate kinase	enzyme_commission	4