Description

An object of class "Anno" that contains associations between Gene Ontology Molecular Function terms and InterPro domains. This data is prepared based on the InterPro database (see http://www.ebi.ac.uk/interpro/) and ftp://anonymous@ftp.ebi.ac.uk/pub/databases/interpro/Current/interpro2go.

Usage

data(InterPro2GOMF)

Value

an object of class Anno. It has slots for "annoData", "termData" and "domainData":

• annoData: a sparse matrix of domains X terms
• termData: variables describing ontology terms (i.e. columns in annoData), including: "ID" (i.e. term ID), "Name" (i.e. term Names), "Namespace" (i.e. term Namespace), and "Distance" (i.e. term Distance to the ontology root)
• domainData: variables describing domains (i.e. rows in annoData), including: "id" for InterPro ID, and "level" always equals "InterPro", "description" for InterPro description

References

Hunter et al. (2012) Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Database (Oxford), 2012:bar068.

Examples

# load data
data(InterPro2GOMF)
InterPro2GOMF

An object of S4 class 'Anno'
@annoData: 8899 domains, 2219 terms 
@termData (InfoDataFrame)
  termNames: GO:0001071 GO:0003824 GO:0004872 ... GO:0015467 GO:0072345
    (2219 total)
  tvarLabels: ID Name Namespace Distance
@domainData (InfoDataFrame)
  domainNames: IPR000003 IPR000006 IPR000008 ... IPR029784 IPR029785
    (8899 total)
  dvarLabels: id level description

# retrieve info on ontology terms
termData(InterPro2GOMF)

An object of S4 class 'InfoDataFrame'
  rowNames: GO:0001071 GO:0003824 GO:0004872 ... GO:0015467 GO:0072345
    (2219 total)
  colNames: ID Name Namespace Distance

# retrieve info on InterPro domains
domainData(InterPro2GOMF)

An object of S4 class 'InfoDataFrame'
  rowNames: IPR000003 IPR000006 IPR000008 ... IPR029784 IPR029785 (8899
    total)
  colNames: id level description

# retrieve the first 5 rows and columns of annotation data
x <- annoData(InterPro2GOMF)[1:5,1:5]
x

5 x 5 sparse Matrix of class "dgCMatrix"
          GO:0004854 GO:0003730 GO:0004855 GO:0004176 GO:0004177
IPR000003          .          .          .          .          .
IPR000006          .          .          .          .          .
IPR000008          .          .          .          .          .
IPR000009          .          .          .          .          .
IPR000010          .          .          .          .          .

# convert the above retrieval to the full matrix
as.matrix(x)

          GO:0004854 GO:0003730 GO:0004855 GO:0004176 GO:0004177
IPR000003          0          0          0          0          0
IPR000006          0          0          0          0          0
IPR000008          0          0          0          0          0
IPR000009          0          0          0          0          0
IPR000010          0          0          0          0          0

See also