Description

An object of class "Anno" that contains associations between UniProtKB KeyWords terms and SCOP domain superfamilies (sf). This data is prepared based on the dcGO database (see http://supfam.org/SUPERFAMILY/dcGO/).

Usage

SCOP.sf2KW <- dcRDataLoader(RData = "SCOP.sf2KW")

Value

an object of class Anno. It has slots for "annoData", "termData" and "domainData":

• annoData: a sparse matrix of domains X terms
• termData: variables describing ontology terms (i.e. columns in annoData), including: "ID" (i.e. term ID), "Name" (i.e. term Names), "Namespace" (i.e. term Namespace), and "Distance" (i.e. term Distance to the ontology root)
• domainData: variables describing domains (i.e. rows in annoData), including: "id" for SCOP sunid, and "level" for SCOP level, "description" for SCOP description

References

Fang H and Gough J. (2013) dcGO: database of domain-centric ontologies on functions, phenotypes, diseases and more. Nucleic Acids Res, 41(Database issue):D536-44.

Examples

# load data
SCOP.sf2KW <- dcRDataLoader(RData='SCOP.sf2KW')

'SCOP.sf2KW' (from http://dcgor.r-forge.r-project.org/data/SCOP.sf2KW.RData) has been loaded into the working environment
SCOP.sf2KW

An object of S4 class 'Anno'
@annoData: 1579 domains, 898 terms 
@termData (InfoDataFrame)
  termNames: KW:0005 KW:0006 KW:0007 ... KW:1112 KW:1224 (898 total)
  tvarLabels: ID Name Namespace Distance
@domainData (InfoDataFrame)
  domainNames: 46458 46548 46557 ... 161240 161256 (1579 total)
  dvarLabels: id level description

# retrieve info on ontology terms
termData(SCOP.sf2KW)

An object of S4 class 'InfoDataFrame'
  rowNames: KW:0005 KW:0006 KW:0007 ... KW:1112 KW:1224 (898 total)
  colNames: ID Name Namespace Distance

# retrieve info on SCOP domains
domainData(SCOP.sf2KW)

An object of S4 class 'InfoDataFrame'
  rowNames: 46458 46548 46557 ... 161240 161256 (1579 total)
  colNames: id level description

# retrieve the first 5 rows and columns of annotation data
x <- annoData(SCOP.sf2KW)[1:5,1:5]
x

5 x 5 sparse Matrix of class "dgCMatrix"
      KW:0695 KW:0696 KW:0697 KW:0001 KW:0003
46458       .       .       .       .       .
46548       .       .       .       1       1
46557       .       .       .       .       .
46561       .       .       .       .       .
46565       .       .       .       .       .

# convert the above retrieval to the full matrix
as.matrix(x)

      KW:0695 KW:0696 KW:0697 KW:0001 KW:0003
46458       0       0       0       0       0
46548       0       0       0       1       1
46557       0       0       0       0       0
46561       0       0       0       0       0
46565       0       0       0       0       0

See also